JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2016, Vol. 54 ›› Issue (12): 82-85.doi: 10.6040/j.issn.1671-7554.0.2016.307

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Analysis on the relationship between urine pH and metabolic syndrome

XU Yibo1, JI Xiaokang2, LI Xiangyi1, SHEN Zhenwei1, XUE Fuzhong1   

  1. 1. Department of Epidemiology and Biostatistics, 2. Information and Data Analysis Lab, School of Public Health, Shandong University, Jinan, 250012, Shandong, China
  • Received:2016-03-22 Online:2016-12-10 Published:2016-12-10

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Abstract: Objective To investigate the correlation of urine pH with metabolic syndrome(MetS). Methods In this study, a longitudinal cohort with 8 720 participants was established based on the routine health check-up systems in Health Management Center of Shandong Provincial Hospital. Cox proportional-hazards model was used to detect the association between urine pH and MetS. Results 1 657 MetS occurred over an average 3.03 years follow-up, leading to a total incidence density of 62.79 per 1 000 person-years(1 657/26 389 person-years). Cox regression analysis by adjusting for age showed that hazard ratio(HR)value of lower urine pH group on MetS was1.36(95%CI: 1.21-1.53, P<0.05). After adjusting for age and four MetS components(hypertension, hyperglycemia, dyslipidemia and obesity)the HR was 1.20(95%CI: 1.07-1.35, P<0.05). After further adjusting for diet, smoking and drinking, the HR was 1.17(95%CI: 1.05-1.32, P<0.05). Conclusion Lower urine pH is an individual risk factor of MetS.

Key words: Insulin resistance, Metabolic acidosis, Cox model, Metabolic syndrome, Urine pH

CLC Number: 

  • R181.3+8
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