JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2015, Vol. 53 ›› Issue (2): 52-55.doi: 10.6040/j.issn.1671-7554.0.2014.235

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Clinical study on the association between metabolic syndrome and P wave dispersion

ZHANG Fenglei, ZHENG Man, ZHANG Qi, GU Lei, XU Xinsheng   

  1. Department of Cardiology, Dongying People's Hospital, Dongying 257091, Shandong, China
  • Received:2014-04-17 Published:2015-02-10

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Abstract: Objective To investigate the effect of metabolic syndrome on P wave dispersion (Pd), in order to reveal its proarrhythmic effect. Methods A total of 86 patients with metabolic syndrome and 102 controls were enrolled in the study. The maximum P wave duration (P max) and minimum P wave duration (P min) were measured with 12-lead synchronous surface electrocardiogram (ECG), and Pd was calculated using P max minus P min. Results Compared with the controls, patients had significantly higher value of Pd (47.31±12.18 vs 33.08±11.04, P=0.001). However, there was no much difference in P max and P min between the two groups (P>0.05). Correlation analyses revealed positive correlation between Pd and body mass index (BMI, P=0.001), total cholesterol (TC, P=0.038), triglyceride (TG, P=0.001), apolipoprotein B (Apo B, P=0.027), systolic blood pressure (SBP, P=0.036) and diastolic blood pressure (DBP, P=0.015). Multiple linear regression analysis indicated distinct association between BMI and Pd (P=0.001). Conclusion BMI is an independent influencing factor of Pd. Controlling metabolic syndrome and BMI will provide a new approach for the prevention and treatment of arrhythmia, especially atrial fibrillation.

Key words: P wave dispersion, Metabolic syndrome, Atrial fibrillation, Electrocardiogram

CLC Number: 

  • R543.3
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