JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2016, Vol. 54 ›› Issue (11): 68-71.doi: 10.6040/j.issn.1671-7554.0.2015.1065

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Introvoxel incoherent motion MR imaging for the assessment of renal function of diabetes mellitus

YU Lu, LIU Qiang   

  1. Shandong Medical Imaging Research Institute of Shandong University, Jinan 250021, Shandong, China
  • Received:2015-11-03 Online:2016-11-10 Published:2016-11-10

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Abstract: Objective To investigate the value of introvoxel incoherent motion magnetic resonance imaging(IVIM-MRI)in evaluating renal function of diabetes mellitus. Methods IVIM-MRI was performed in 20 cases of diabetes mellitus(diabetic group)and 20 healthy controls(control group)using 3.0T MR system. The differences of diffusion coefficient(D), perfusion fraction(f), and pseudodiffusion coefficient(D*)were compared. Results D and f values of renal cortex of the diabetic group were significantly higher than those of the control group(t=2.187, P=0.035; t=2.334, P=0.025). D and f values of renal medulla of the diabetic group were higher than those of control group, but with no significant differences(t=1.753, P=0.088; t=0.682, P=0.499). D* values of renal medulla and cortex of the diabetic group were higher than those of the control group, but without significant differences(t=0.088, P=0.93; t=0.592, P=0.557). D, f, D* values of renal medulla were significantly different from those of renal cortex in both diabetic and control groups(diabetes mellitus group t=9.64, P=0.002; t=12.163, P=0.001; t=15.993, P=0.001; control group t=11.228, P=0.001; t=12.055, P=0.001; t=14.708, P=0.001). Conclusion Introvoxel incoherent motion MR imaging can evaluate the renal function of diabetic patients non-invasively.

Key words: Diabetes mellitus, Renal function, Perfusion fraction, Introvoxel incoherent motion MR imaging, Diffusion coefficient

CLC Number: 

  • R587.1
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