JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES)

• Articles • Previous Articles     Next Articles

Characterization of hearing loss in aged type 2 diabetics and its correlation factors

FAN Yun-xia1, HAN Feng2, CUI Xiao-kang1, DONG Ming1 XIAO Xiao-yan1, XU An-ting3, REN Jian-min1

  

  1. 1. Department of Endocrinology, Qilu Hospital of Shandong University, Jinan 250012, China; 2. Department of Endocrinology, Zhangqiu People′s Hospital, Jinan 250200, China; 3. Department of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan 250012, China

  • Received:1900-01-01 Revised:1900-01-01 Online:2008-07-16 Published:2008-07-16
  • Contact: REN Jian-min

Abstract:

Objective〓〖WTBZ〗To study the characteristics of hearing loss in aged type 2 diabetics and to explore its correlation factors. 〖WTHZ〗Methods〓〖WTBZ〗118 aged type 2 diabetics and 50 controls were enrolled in this study. Pure-tone audiometry, distortion product otoacoustic emissions (DPOAE) and auditory brainstem responses (ABR) were determined. 〖WTHZ〗Results〓〖WTBZ〗① Logistic regressive analysis showed that independent risk factors associated with hearing loss of the aged type 2 diabetics were age,course of the T2DM, LDL-C , diabetic nephropathy and diabetic retinopathy; ② The pure-tone audiometry test showed that there was a great deficit at high frequencies in the two groups, and a stronger tendency of affecting the right ear than the left; ③ The DPOAE test showed that the amplitude of DPOAE in diabetics was decreased compared with the control group, and a stronger tendency of affecting the right ear than the left ear(P<0.05); ④ The ABR test showed that latencies of wavesⅢ,Ⅴand interwaveⅠ-Ⅲ of 40dB above the auditory threshold were longer in diabetics(P<0.05), and there was no statistical significance between the left ear and the right. 〖WTHZ〗Conclusions〓〖WTBZ〗Hearing impairment in aged type 2 diabetics is significant at high frequencies, especially in the right ear. Age, course of the T2DM and LDL-C and diabetic micrangium complications are the risk factors.

Key words: Diabetes mellitus, non-insulin-dependent, Risk factors, Hearing loss, Audiometry

CLC Number: 

  • R587.2
[1] SUN Qijing, CHEN Fangfang, LI Chunxiao, ZHANG Caiqing. Clinical value of PNI and HGB in evaluating the prognosis of the middle to late stage non-small cell lung cancer patients [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(4): 55-59.
[2] LI Shuai, WANG Yalin, SUN Zhongwen, ZHU Meijia. Expression changes and mechanism of Nod-like receptor protein 3 inflammasome in the cerebral microvascular endothelial cells in type 2 diabetes mellitus [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(3): 6-11.
[3] DU Heng, YUAN Xiaodong. Progress in the etiology and pathogenesis of Alzheimers disease [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(10): 21-27.
[4] QIU Chengxuan, DU Yifeng. A call for action to strengthen research on population interventions against Alzheimers disease and senile dementia [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(10): 1-6.
[5] PENG Li, QIANG Ye, ZHAO Huichen, CHEN Shihong, YAO Weidong, LIU Yuantao. Clinical studies on type 2 diabetic patients treated with sitagliptin [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(8): 60-63.
[6] LIN Dong, GUAN Qingbo. Association of serum testosterone level and non-alcoholic fatty liver disease in male patients with T2DM [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(7): 33-37.
[7] WANG Yihua, MA Lin, KAN Yanmin, WANG Wentao. Early ultrasound observation of uterine incision defect after cesarean section and analysis of related factors [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(5): 39-44.
[8] Muhadasi TUERXUNYIMING, Patamu MOHEMAITI, Tuolanguli MAIMAITIKUERBAN. Association of CDKAL1 rs10946398 C/A polymorphism with type 2 diabetes [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(2): 75-85.
[9] YU Ning, GAO Yanyan, XIAN Yuxin, NIU Jiapeng, LI Li, WANG Jing, CAO Caixia. Effect of exenatide on serum chemerin level and liver fat contents in type 2 diabetes mellitus combined with non-alcoholic fatty liver disease patients [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(11): 51-55.
[10] YU Lu, LIU Qiang. Introvoxel incoherent motion MR imaging for the assessment of renal function of diabetes mellitus [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(11): 68-71.
[11] YIN Xiaofang, GE Haibo. Epidemiological features of inpatients suffered from pulmonary tuberculosis with diabetes mellitus [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(1): 58-61.
[12] ZHANG Dongqing, WANG Yong, CHEN Shouzhen, ZHU Yaofeng, SHI Benkang. Changes on the expressions of alpha1-adrenergic receptor and nerve growth factor and their effects on urethral function in diabetic rats [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2015, 53(9): 30-34.
[13] LIU Yanxun, LIU Jia, ZHANG Tao, WANG Lu, XUE Fuzhong, WANG Ping. Type 2 diabetes mellitus associated with thyroid nodules: a longitudinal health check-up cohort study [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2015, 53(8): 83-86.
[14] YOU Jiebing, SUN Zhongwen, DU Juan, XU Wenjuan, WANG Yalin, LI Shuai, ZHU Meijia. Effects of rosiglitazone and insulin on the expression of TIPE2 and cell apoptosis in the brain of type 2 diabetic GK rats [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2015, 53(4): 43-48.
[15] PEI Leilei, SUN Zhonghua, LI Zhe, ZHAO Wenping. Effects of sitagliptin combined with high-dose insulin on type 2 diabetes mellitus [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2015, 53(2): 39-42.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!