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山东大学学报 (医学版) ›› 2024, Vol. 62 ›› Issue (7): 106-113.doi: 10.6040/j.issn.1671-7554.0.2024.0510

• 公共卫生与预防医学 • 上一篇    下一篇

2018-2022年某县镉和铅多暴露途径的健康风险评估

王苏玮,刘毅刚,安玉琴,袁树华,郝海燕,丁婷婷   

  1. 河北省疾病预防控制中心环境卫生监测与评价所, 河北 石家庄 050021
  • 发布日期:2024-09-20
  • 通讯作者: 丁婷婷. E-mail:dingtingting1028@hebmail.gov.cn
  • 基金资助:
    2021年河北省医学科学研究重点课题计划项目(20210098)

Health risk assessment of cadmium and lead in a certain county with multi-pathways from 2018 to 2022

WANG Suwei, LIU Yigang, AN Yuqin, YUAN Shuhua, HAO Haiyan, DING Tingting   

  1. Environmental Health Monitoring and Evaluation Institute, Hebei Province Center for Disease Prevention and Control, Shijiazhuang 050021, Hebei, China
  • Published:2024-09-20

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摘要： 目的 评估某县大气细颗粒物(PM2.5)、饮用水、土壤中镉和铅的人群健康风险。 方法 收集2018—2022年某县大气PM2.5、饮用水、土壤中镉和铅的监测数据,运用环境健康风险评估模型分析镉和铅浓度中位数的致癌风险和慢性非致癌风险。分析不同暴露途径占比情况和不同年份结果的变化。 结果 镉和铅的致癌风险为8.02×10-7、2.50×10-7,均小于1×10-6,处于可接受水平。镉和铅慢性非致癌风险为6.95×10-2、1.09×10-2,危害系数均小于1,不会造成显著损害。不同暴露途径的致癌风险对比,镉、铅为大气PM2.5吸入途径占比最高。不同途径的慢性非致癌风险对比,镉为大气PM2.5吸入途径占比最高,铅为饮用水经口摄入途径占比最高。2022年镉和铅致癌风险和慢性非致癌风险均比2018年有所下降。 结论 2018—2022年某县镉、铅的健康风险处于可接受水平,不同途径的健康风险对比中,空气PM2.5吸入途径占比最高,应加强当地大气PM2.5监测与污染管理。

关键词: 镉, 铅, 健康风险评估, 大气细颗粒物, 饮用水, 土壤, 多暴露途径

Abstract: Objective To evaluate the health risks of cadmium and lead in air fine particulate(PM2.5), drinking water, and soil of a certain county. Methods The monitoring data of cadmium and lead in the air PM2.5, drinking water, and soil of a certain county from 2018 to 2022 were collected. The environmental health risk assessment model was applied to evaluate both carcinogenic risk and chronic non-carcinogenic risk caused by median concentration of cadmium and lead. The proportion of different exposure routes and the change of results in different years were analyzed. Results The carcinogenic risk values were 8.02×10-7 for cadmium, and 2.50×10-7 for lead, which were less than 1×10-6 and at an acceptable level. The chronic non-carcinogenic risk values were 6.95×10-2 for cadmium, and 1.09×10-2 for lead. The hazard coefficients were less than 1 and had no significant harm. The comparison of carcinogenic risks through different pathways showed that cadmium and lead had the highest proportion of PM2.5 inhalation in the air. The comparison of chronic non-carcinogenic risks through different pathways showed that cadmium had the highest proportion of inhalation pathways in air PM2.5, while lead had the highest proportion of oral intake pathways in water. The carcinogenic and chronic non-carcinogenic risks of cadmium and lead were both lower in 2022 than in 2018. Conclusion From 2018 to 2022, the chronic non-carcinogenic risks and carcinogenic risks of cadmium and lead were at an acceptable level in the county. The proportion of PM2.5 inhalation route was the highest in the comparison of health risk of different routes, so the monitoring and pollution management of PM2.5 should be strengthened.

Key words: Cadmium, Lead, Health risk assessment, Fine particulate, Drinking water, Soil, Multi-pathways

中图分类号: 

  • R12
[1] 支敏康. 2016和2020年北京市冬季不同粒径大气颗粒物中金属元素的分布与风险评估比较研究[D]. 北京:中国环境科学研究院, 2022.
[2] 赵秀阁.典型地区居民金属环境总暴露影响因素研究及健康风险评估[D]. 兰州: 兰州大学, 2023.
[3] 张盈盈,岳帅,杜艳君,等. 2017年某地重金属多介质多暴露途径的健康风险评估[J]. 山东大学学报(医学版), 2021, 59(12):127-133,142. ZHANG Yingying, YUE Shuai, DU Yanjun, et al. Health risk assessment of heavy metals in multi-pathways in a certain area in 2017[J]. Journal of Shandong University(Health Sciences), 2021, 59(12):127-133,142.
[4] WHO/IARC. IARC monographs on the identification of carcinogenic hazards to human [R/OL].(2024-01-04)[2024-06-17]. https://monographs.iarc.who.int/list-of-classifications.
[5] IRIS. IRIS assessments[R/OL].(2024-01-04)[2024-06-17]. https://iris.epa.gov/AtoZ/?list_type=alpha.
[6] CALEPA. Toxicity criteria on chemicals evaluated by OEHHA, chemicals search[R/OL].(2024-01-04)[2024-06-17]. https://oehha.ca.gov/chemicals.
[7] 张翼, 王情, 王苏玮, 等. 我国环境健康风险评估指南编制的思考[J]. 环境与健康杂志, 2019, 36(12): 1046-1048. ZHANG Yi, WANG Qing, WANG Suwei, et al. Thoughts on compilation of guidelines for environmental health risk assessment in China[J]. Journal of Environment and Health, 2019, 36(12): 1046-1048.
[8] 中华人民共和国国家卫生健康委员会. 化学物质环境健康风险评估技术指南:WS/T 777—2021[S]. 北京:中国标准出版社, 2021.
[9] 韩嘉艺, 叶必雄, 张岚. 某市饮用水中10种污染物的健康风险评价[J]. 环境卫生学杂志, 2019, 9(3): 203-209. HAN Jiayi, YE Bixiong, ZHANG Lan. Health risk assessment of 10 pollutants in a city’s drinking water [J]. Journal of Environmental Hygiene, 2019, 9(3): 203-209.
[10] 中华人民共和国国家生态环境部. 中华人民共和国国家环境保护标准:环境空气质量手工监测技术规范HJ 194—2017 [S/OL].(2017-12-29)[2024-01-04]. https://www.mee.gov.cn/ywgz/fgbz/bz/bzwb/jcffbz/201801/W020180108573132220085.pdf.
[11] 中华人民共和国卫生部. 中华人民共和国国家标准:生活饮用水标准检验方法水样的采集与保存GB/T 5750.2—2006[S/OL].(2006-12-29)[2024-01-04]. http://www.nhc.gov.cn/cm-sresources/zwgkzt/wsbz/new/20070628150039.pdf.
[12] 中华人民共和国国家生态环境部. 中华人民共和国环境保护行业标准:土壤环境监测技术规范HJ/T 166—2004[S/OL].(2004-12-09)[2024-01-04]. https://www.mee.gov.cn/gkml/zj/wj/200910/t20091022_172314.htm.
[13] 中华人民共和国国家生态环境部. 中华人民共和国国家标准:环境空气质量标准 GB3095—2012[S]. 北京: 中国环境出版社, 2012.
[14] 中华人民共和国卫生部, 中国国家标准化管理委员会. 生活饮用水卫生标准: GB 5749—2006 [S]. 北京: 中国标准出版社, 2007.
[15] 中华人民共和国国家生态环境部. 土壤环境质量农用地土壤污染风险管控标准(试行)GB 15618—2018 [S/OL].(2018-06-22)[2024-01-04]. https://www.mee.gov.cn/ywgz/fgbz/ bz/bzwb/trhj/201807/t20180703_446029.shtml.
[16] United States Enviromental Protection Agency. Risk Assessment Guidance for Superfund Volume I: Human Health Evaluation Manual(Part E, Supplemental Guidance for Dermal Risk Assessment)Final[R]. Washington, DC, USA:U.S. Environmental Protection Agency, 2004.
[17] Du YJ, Zhao L, Ban J, et al. Cumulative health risk assessment of disinfection by-products in drinking water by different disinfection methods in typical regions of China[J]. Sci Total Environ, 2021, 770: 144662. doi:10.1016/j.scitotenv.2020.144662.
[18] 中华人民共和国国家生态环境部. 中国人群暴露参数手册(成人卷)[M]. 北京:中国环境科学出版社, 2013.
[19] Agency for Toxic Substances and Disease Registry. Minimal Risk Levels(MRLs)for Hazardous Substances [R/OL].(2024-01-04)[2024-06-17]. https://wwwn.cdc.gov/TSP/MRLS/mrlsListing.aspx.
[20] Yu PY, Han YL, Wang MD, et al. Heavy metal content and health risk assessment of atmospheric particles in China: a meta-analysis[J]. Sci Total Environ, 2023, 867: 161556. doi:10.1016/j.scitotenv.2023.161556.
[21] 李友平, 刘慧芳, 周洪, 等. 成都市PM2.5中有毒重金属污染特征及健康风险评价[J]. 中国环境科学, 2015, 35(7): 2225-2232. LI Youping, LIU Huifang, ZHOU Hong, et al. Contamination characteristics and health risk assessment of toxic heavy metals in PM2.5 in Chengdu[J]. China Environmental Science, 2015, 35(7): 2225-2232.
[22] 王燕, 高衍新, 李仁波, 等. 济南市大气PM2.5铅污染特征、变化趋势与风险评估[J]. 环境与职业医学, 2023, 40(7): 811-816. WANG Yan, GAO Yanxin, LI Renbo, et al. Pollution characteristics, long-term variation trend, and health risk assessment of lead in ambient PM2.5 in Jinan[J]. Journal of Environmental and Occupational Medicine, 2023, 40(7): 811-816.
[23] 岳宣志, 李欢, 高昇, 等. 2021年内蒙古自治区农村饮用水砷、镉、铬、铅和汞健康风险评估[J]. 环境卫生学杂志, 2023, 13(10): 765-769, 777. YUE Xuanzhi, LI Huan, GAO Sheng, et al. Health risk assessment of arsenic, cadmium, chromium, lead and mercury in rural drinking water in Inner Mongolia Autonomous Region, China, 2021[J]. Journal of Environmental Hygiene, 2023, 13(10): 765-769, 777.
[24] 郭日, 张盈盈, 臧加伟, 等. 中国十省市土壤重金属镉生态风险和健康风险评估[J]. 环境卫生学杂志, 2023, 13(9): 680-685, 695. GUO Ri, ZHANG Yingying, ZANG Jiawei, et al. Ecological and health risk assessment of cadmium in soil of ten provinces and cities, China[J]. Journal of Environmental Hygiene, 2023, 13(9): 680-685, 695.
[25] 李志. 广州市灰尘、土壤重金属污染特征及其健康风险评估[D]. 广州:广州大学, 2022.
[26] 王珊, 魏海春. 2018年我国中东部局部地区农田土壤典型重金属健康风险评估[J]. 环境与健康杂志, 2019, 36(9): 807-810. WANG Shan, WEI Haichun. Health risk assessment of typical heavy metals in farmland soils in parts of central and Eastern China in 2018[J]. Journal of Environment and Health, 2019, 36(9): 807-810.
[27] 王苏玮, 丁婷婷, 安玉琴, 等. 河北省市政供水三氯甲烷和四氯化碳的健康风险[J]. 环境卫生学杂志, 2023, 13(7): 524-529, 536. WANG Suwei, DING Tingting, AN Yuqin, et al. Health risk of chloroform and carbon tetrachloride in municipal water supply in Hebei Province, China[J]. Journal of Environmental Hygiene, 2023, 13(7): 524-529, 536.
[28] 龙新宪,刘文晶,仇荣亮.中国农田土壤重金属污染的人体健康风险评估:研究进展与展望[J].土壤学报,2024, 61(5). doi:10.11766/trxb202306130229. LONG Xinxian, LIU Wenjing, QIU Rongliang. Research progress and prospects of human health risk assessment of heavy metal pollution in farmland soils of China[J]. Acta Pedologica Sinica, 2024, 61(5). doi:10.11766/trxb202306130229.
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