Journal of Shandong University (Health Sciences) ›› 2021, Vol. 59 ›› Issue (5): 1-7.doi: 10.6040/j.issn.1671-7554.0.2021.0319

• Current Advance of Basic and Clinical Medical Virology •     Next Articles

Research progress on factors influencing the protective effects of influenza vaccines

Yuelong SHU*(),Simin WEN   

  1. School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen 518107, Guangdong, China
  • Received:2021-03-24 Online:2021-05-10 Published:2021-06-01
  • Contact: Yuelong SHU E-mail:shuylong@mail.sysu.edu.cn

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Abstract:

Annual vaccination is the best prevention of influenza. However, the protective effects of influenza vaccines currently used are poor due to variation of influenza viruses. The protective effects can also be affected by other factors including the genetic factor, and it is important to fully identify these related factors. In this paper, we briefly summarized the factors that may influence the protective effects of influenza vaccines from the aspects of the matching degree of circulating strains and vaccine strains, vaccine factors and host factors, and proposed the development direction of new influenza vaccines in the future.

Key words: Influenza vaccine, Protective effect, Vaccine factors, Host factors

CLC Number: 

  • R186
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