JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2015, Vol. 53 ›› Issue (10): 66-72.doi: 10.6040/j.issn.1671-7554.0.2015.299

Previous Articles     Next Articles

Meta-analysis of the prognosis of prenatally-diagnosed fetal agenesis of corpus callosum

WANG Yin1, MA Zhe2, TAO Guowei2, LIU Shaoping2, DING Tingting2, SHI Linlin2   

  1. 1. Department of Ultrasound, Xijing Hospital of Fourth Medical Military Medical University, Xi'an 710032, Shaanxi, China;
    2. Department of Ultrasound, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Received:2015-03-20 Online:2015-10-10 Published:2015-10-10

PDF (PC)

405

Abstract: Objective To explore the outcomes of agenesis of corpus callosum (ACC), and to compare the prognosis of isolated ACC with ACC complicated with other abnormalities. Methods Literature about the prognosis of ACC during 1990 to 2012 were retrieved and Meta-analysis was conducted. Results A total of 15 studies involving 565 cases were included. The overall rate of terminations was 65%. There was a higher incidence of ACC in males than in females, with the pooled RR=1.29, 95%CI=1.04-1.59, P<0.05. The overall rate of favorable prognosis for simple ACC was up to 70%, while that of ACC complicated with structural anomalies was 16%. There was statistical difference between the two values, the pooled OR=0.07, 95%CI=0.02-0.24, P<0.05. Conclusion There is a high rate of terminations due to prenatal diagnosis of fetal agenesis of corpus callosum. The incidence of ACC is higher in males than in females. The prognosis of isolated ACC is favorable, while the prognosis of ACC complicated with other anomalies is poor.

Key words: Prognosis, Agenesis of corpus callosum, Meta-analysis

CLC Number: 

  • R455.1
[1] Pati M, Cani C, Bertucci E, et al. Early visualization and measurement of the pericallosal artery: an indirect sign of corpus callosum development[J]. Ultrasound Med, 2012, 31(2): 231-237.
[2] Nq WH, Chan YL, Au KS, et al. Morphometry of the corpus callosum in Chinese children: relationship with gender and academic performance[J]. Pediatr Radiol, 2005, 35(6): 565-571.
[3] Fratelli N, Papageorghiou AT, Prefumo F, et al. Outcome of prenatally diagnosed agenesis of the corpus callosum[J]. Prenat Diagn, 2007, 27(6): 512-517.
[4] 张天嵩, 钟文昭, 张素, 等. Stata在Meta分析时异质性评价中的应用[J].循证医学, 2008, 4(8): 231-234. ZHANG Tiansong, ZHONG Wenzhao, ZHANG Su, et al. Stata in assessing heterogeneity in meta-analysis[J]. J The Journal of Evidence-Based Medicine, 2008, 4(8): 231-234.
[5] Pilu G, Sandri F, Perolo A, et al. Sonography of fetal agenesis of the corpus callosum: a survey of 35 cases[J]. Ultrasound Obstet Gynecol, 1993, 3(5): 318-329.
[6] Vergnai P, Ghidini A, Strobelt N, et al. Prognostic indicators in the prenatal diagnosis of agenesis of corpus callosum[J]. Am J Obstet Gynecol,1994,170(3): 753-758.
[7] Erocle C, Girard N, Cravello L, et al. Prenatal diagnosis of fetal corpus callosum agenesis by ultrasonography and magnetic resonance imaging[J]. Prenat Diagn, 1998,18(3): 247-253.
[8] Moutard M, Kieffer V, Feiggold J, et al. Agenesis of corpus callosum: prenatal diagnosis and prognosis[J]. Childs Nerv Syst, 2003,19(7-8): 471-476.
[9] Glenn OA, Goldstein RB, Li KC, et al. Fetal magnetic resonance imaging in the evaluation of fetuses referred for sonographically suspected abnormalities of the corpus callosum[J]. J Ultrasound Med, 2005, 24(6): 791-804.
[10] Ramelli G, Zanda N, Wyttenbach M, et al. The prognosis of agenesis of the corpus callosum might mostly be favourable[J]. Swiss Med Wkly, 2006, 24(25-26): 404-405.
[11] Francesco P, Maria-Edqarda B, Giovanni P, et al. Prenatal diagnosis of agenesis of corpus callosum: what is the neurodevelopmental outcome?[J]. Pediatr Int, 2006, 48(3): 298-304.
[12] Volpe P, Paladini D, Resta M, et al. Characteristics, associations and outcome of partial agenesis of the corpus callosum in the fetus[J]. Ultrasound Obstet Gynecol, 2006, 27(5): 509-516.
[13] Chadie A, Radi S, Trestard L, et al. Neurodevelopmental outcome in prenatally diagnosed isolated agenesis of the corpus callosum[J]. Acta Paediatr, 2008, 97(4): 420-424.
[14] Ghi T, Carletti A, Contro E, et al. Prenatal diagnosis and outcome of partial agenesis and hypoplasia of the corpus callosum[J]. Ultrasound Obstet Gynecol, 2010, 35(1): 35-41.
[15] Mangione R, Fries N, Godard P, et al. Neurodevelopmental outcome following prenatal diagnosis of an isolated anomaly of the corpus callosum[J]. Ultrasound Obstet Gynecol, 2011, 37(3): 290-295.
[16] Mountard ML, Kieffer V, Feingold J, et al. Isolated corpus callosum agenesis: a ten-year follow-up after prenatal diagnosis (how are the children without corpus callosum at 10 years of age?)[J]. Prenat Diagn, 2012, 32(3): 277-283.
[17] 杨杰, 谢红宁, 何花, 等. 胎儿胼胝体发育不全与合并其他异常的相关性[J]. 中国实用妇科与产科杂志, 2009, 1(25): 37-39. YANG Jie, XIE Hongning, HE Hua, et al. Prenatal diagnosis of fetal agenesis of corpus callosum and its association with other abnormalities[J]. Chinese Journal of Practical Gynecology and Obstetrics, 2009, 1(25): 37-39.
[18] 程桂静, 杨太珠, 徐红, 等. 胎儿胼胝体发育不全的超声诊断及临床分析[J]. 中国超声医学杂志, 2012, 6(28): 549-552. CHENG Guijing, YANG Taizhu, XU Hong, et al. The ultrasonographic diagnosis of fetal corpus callosum agenesis and clinical analysis[J]. Chinese J Ultrasound Med, 2012, 6(28): 549-552.
[19] Vasudevan C, Mckechnie L, Levene M, et al. Long-term outcome of antenatally diagnosed agenesis of corpus callosum and cerebellar malformations[J]. Semin Fetal Neonatal Med, 2012, 17(5): 295-300.
[20] Yang Y, Phillips OR, Kan E, et al. Callosal thickness reductions relate to facial dysmorphology in fetal alcohol spectrum disorders[J]. Alcohol Clin Exp Res, 2012, 36(5): 798-806.
[21] Goodyear PW, Bannister CM, Russell S, et al. Outcome in prenatally diagnosed fetal agenesis of the corpus callosum[J]. Fetal Diagn Ther, 2001, 16(3): 139-145.
[1] LI Yinglin, SONG Daoqing, XU Zhonghua. Identification of FKBP11 expression in clear cell renal cell carcinoma using bioinformatics analysis [J]. Journal of Shandong University (Health Sciences), 2020, 1(9): 45-51.
[2] SHI Shuang, LI Juan, MI Qi, WANG Yunshan, DU Lutao, WANG Chuanxin. Construction and application of a miRNAs prognostic risk assessment model of gastric cancer [J]. Journal of Shandong University (Health Sciences), 2020, 1(7): 47-52.
[3] LI Xingkai, LIU Zhanye, JIANG Yunfeng, LI Jun. Clinicopathological factors and prognosis between primary central and peripheral lung squamous cell carcinoma [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(9): 73-78.
[4] LIN Pingzhen, XUE Jiaomei, YANG Bei, LI Meng, ZHOU Mailin, CAO Fenglin. Correlation between posttraumatic growth and psychological adjustment of cancer survivors based on Pearson correlation coefficient: a Meta-analysis [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(9): 110-121.
[5] ZONG Shuai, XIAO Dongjie, LIU Hua, JIA Yanfei, MA Xiaoli, LI Huanjie, LI Ping, ZHENG Yan, WANG Yunshan. Expression of CSN5 and its correlation with the prognosis of gastric carcinoma [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(7): 12-16.
[6] DU Jinge, CHEN Hui, YANG Xiaorong, LÜ Ming. Meta-analysis of the association between the STAT4 rs7574865 polymorphism and systemic lupus erythematosus [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(5): 95-102.
[7] SUN Qijing, CHEN Fangfang, LI Chunxiao, ZHANG Caiqing. Clinical value of PNI and HGB in evaluating the prognosis of the middle to late stage non-small cell lung cancer patients [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(4): 55-59.
[8] LIN Jiaxiang, GUO Zijia, SU Peng, WANG Xiao, GUO Yaxin, WU Xiaojuan, XIANG Lei, ZHOU Zhiqiang, WANG Yan, CUI Xiujie, PAN Aifeng, GUO Chenghao. The role of CIP2A in the transformation of breast ductal epithelium and prognosis of invasive breast cancer [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(3): 100-106.
[9] ZHOU Lanlan, PAN Xueyi, GUO Yu. Clinical characteristics and prognosis of 48 patients with mixed phenotype acute leukemia [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(2): 79-83.
[10] ZHANG Xiying, ZHAI Chunyan, LI Jingsong, HAN Bo. Expression of EZH2 in Chinese Ewing sarcoma patients and its relationship with clinicopathological parameters and prognosis [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(2): 84-91.
[11] LIU Huiling, WANG Xingwen, FENG Shaobin, FENG Hong, HAN Junqing. Association between high expression of scavenger receptor class B type I and the prognosis of colon cancer [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(10): 84-89.
[12] WANG Lili, HUO Bin, WANG Lei, WANG Hao, HOU Dingkun, HUO Xiaodong, WANG Jinhuan, ZANG Li, CAO Qiang, CHAI Shude, WANG Haitao. Meta-analysis and system evaluation of 125I implantation in the treatment of early lung cancer [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(10): 76-83.
[13] LI Xiaoning, CUI Lianqun. Treatment timing of non-infarct-related artery in patients with multi-vessel disease and acute myocardial infarction [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(8): 50-54.
[14] WANG Wen, LIU Yao, LONG Fei, MA Weixia, SU Lili. Correlation between lymphocyte-to-monocyte ratio in peripheral blood and prognosis of malignant pleural mesothelioma [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(8): 72-77.
[15] LIU Tong, ZHANG Xin, WANG Chuanxin. Significance of IRX5 mRNA in the diagnosis and prognosis of colorectal cancer [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(7): 69-74.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Copyright 2018 © Editorial office of Journal of Shandong University (Health Sciences)
Supported by Beijing Magtech Co.Ltd