Journal of Shandong University (Health Sciences) ›› 2019, Vol. 57 ›› Issue (3): 38-41.doi: 10.6040/j.issn.1671-7554.0.2019.053

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Chemical constituents of Chiloscyphus polyanthus var. rivularis

ZHANG Jiaozhen, LOU Hongxiang   

  1. Key Lab of Chemical Biology(Ministry of Education), Department of Natural Products Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, Shandong, China
  • Published:2022-09-27

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Abstract: Objective To study the chemical constituents of Chiloscyphus polyanthus var. rivularis. Methods The chemical constituents were isolated and identified on the basis of various chromatographic methods such as MCI gel, silica gel, Sephadex LH-20 column, and semi-preparation HPLC as well as a combination of their spectroscopic data, such as NMR and HRESIMS. Results Isolation of Chiloscyphus polyanthus var. rivularis afforded five compounds, including two new eudesmane type sesquiterpenoids, which were named (3S,7R,10S)-7-hydroxy-3-methoxy-eudesma-4E-ene(1)and (3S,7R,10S)-7-hydroxy-3-ethyoxyl-eudesma-4E-ene(2), one guaiane type sesquiterpenoid(guaianediol, 3), one labdane-type diterpenoid(nivenolide, 4), and one triterpenoid(betulin, 5). Conclusion Compounds 1 and 2 are previously undescribed and compounds 3-5 are isolated from the plants in genus Chiloscyphus for the first time.

Key words: Bryophytes, Chiloscyphus polyanthus var. rivularis, Eudesmane type sesquiterpenoids, Guaiane type sesquiterpenoid, Diterpenoid, Triterpenoid

CLC Number: 

  • R574
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