Journal of Shandong University (Health Sciences) ›› 2018, Vol. 56 ›› Issue (12): 98-102.doi: 10.6040/j.issn.1671-7554.0.2018.412

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Epidemiological and clinical analysis of 74 cases of severe fever with thrombocytopenia syndrome in Shandong Province, China from 2014 to 2015

SUN Luyan, ZHANG Xiuzhen, LIU Kuihua, YANG Bo, WU Anzhao, YUAN Chengmin   

  1. Department of Traditional Chinese and Western Medicine, Jinan Infectious Disease Hospital, Jinan 250021, Shandong, China
  • Published:2022-09-27

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Abstract: Objective To summarize and analyze the epidemiological features and clinical characteristics of severe fever with thrombocytopenia syndrome(SFTS). Methods The clinical data of 74 patients with SFTS in Shandong Province were collected and retrospectively analyzed. They accepted treatment in Jinan Infectious Disease Hospital from 2014 to 2015. The data included epidemiology, clinical symptoms, signs and related laboratory tests. Results The disease occurred mostly in the elderly farmers living in hilly areas. Some patients had tick bites history. The clinical manifestations included fever, systemic symptoms and digestive system symptoms, and some severe patients also had pneumonia, gastrointestinal bleeding and multiple organ damage, etc. After antiviral and symptomatic treatments, 46 cases were cured; 12 died during hospitalization; and 16 gave up treatment and left hospital voluntarily,and among them 13 died during follow-up. Conclusion SFTS progresses rapidly and has a high fatality rate. It is necessary to strengthen the awareness of disease prevention,and early diagnosis and treatment are the most important measures.

Key words: Severe fever with thrombocytopenia syndrome, Fever, Thrombocytopenia

CLC Number: 

  • R574
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