您的位置:山东大学 -> 科技期刊社 -> 《山东大学学报(医学版)》

山东大学学报 (医学版) ›› 2024, Vol. 62 ›› Issue (7): 56-61.doi: 10.6040/j.issn.1671-7554.0.2024.0587

• 呼吸系统疾病精准诊疗专题 • 上一篇    下一篇

重症新型冠状病毒肺炎伴侵袭性肺曲霉病及反复致命性消化道出血1例

张学宇1,张学海1,孙文青2,刘晗3,姜金波4,刘寒1,李远1,陈晓梅1   

  1. 1.山东大学齐鲁医院重症医学科, 山东 济南 250012;2.山东省公共卫生临床中心重症医学科, 山东 济南 250100;3.山东大学齐鲁医院消化内科, 山东 济南 250012;4.山东大学齐鲁医院普外科, 山东 济南 250012
  • 发布日期:2024-09-20
  • 通讯作者: 陈晓梅. E-mail:chenxm008@163.com
  • 基金资助:
    山东省医学会科研基金(YXH2020ZX044)

  • Published:2024-09-20

关键词: 新型冠状病毒感染, 重症肺炎, 侵袭性肺曲霉病, 巨细胞病毒结肠炎, 消化道出血, 诊断, 治疗

中图分类号: 

  • R511
[1] Hoenigl M, Seidel D, Sprute R, et al. COVID-19-associated fungal infections[J]. Nat Microbiol, 2022, 7(8): 1127-1140.
[2] Abdoli A, Falahi S, Kenarkoohi A. COVID-19-associated opportunistic infections: a snapshot on the current reports[J]. Clin Ex Med, 2022, 22(3): 327-346.
[3] Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019(COVID-19)outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention[J]. JAMA, 2020, 323(13): 1239-1242.
[4] Koehler P, Bassetti M, Chakrabarti A, et al. Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance[J]. Lancet Infect Dis, 2021, 21(6): e149-e162.
[5] Feys S, Lagrou K, Lauwers HM, et al. High burden of COVID-19-associated pulmonary aspergillosis in severely immunocompromised patients requiring mechanical ventilation[J]. Clin Infect Dis, 2024, 78(2): 361-370.
[6] Apostolopoulou A, Esquer Garrigos Z, Vijayvargiya P, et al. Invasive pulmonary aspergillosis in patients with SARS-CoV-2 infection: a systematic review of the literature[J]. Diagnostics(Basel), 2020, 10(10): 807. doi: 10.3390/diagnostics10100807.
[7] Arastehfar A, Carvalho A, van de Veerdonk FL, et al. COVID-19 associated pulmonary aspergillosis(CAPA)—from immunology to treatment[J]. J Fungi(Basel), 2020, 6(2): 91. doi: 10.3390/jof6020091.
[8] Dellière S, Dudoignon E, Fodil S, et al. Risk factors associated with COVID-19-associated pulmonary aspergillosis in ICU patients: a French multicentric retrospective cohort[J]. Clin Microbiol Infect, 2021, 27(5): 790.e1-790.e5.
[9] Salmanton-García J, Sprute R, Stemler J, et al. COVID-19-associated pulmonary aspergillosis, March-August 2020[J]. Emerg Infect Dis, 2021, 27(4):1077-1086.
[10] Hashim Z, Nath A, Khan A, et al. Effect of glucocorticoids on the development of COVID-19-associated pulmonary aspergillosis: a meta-analysis of 21 studies and 5174 patients[J]. Mycoses, 2023, 66(11): 941-952.
[11] Leistner R, Schroeter L, Adam T, et al. Corticosteroids as risk factor for COVID-19-associated pulmonary aspergillosis in intensive care patients[J]. Crit Care, 2022, 26(1): 30. doi: 10.1186/s13054-022-03902-8.
[12] WHO Rapid Evidence Appraisal for COVID-19 Therapies(REACT)Working Group, Sterne JAC, Murthy S, et al. Association between administration of systemic corticosteroids and mortality among critically Ill patients with COVID-19: a Meta-analysis[J]. JAMA, 2020, 324(13): 1330-1341.
[13] Alexander BD, Lamoth F, Heussel CP, et al. Guidance on imaging for invasive pulmonary aspergillosis and mucormycosis: from the imaging working group for the revision and update of the consensus definitions of fungal disease from the EORTC/MSGERC[J]. Clin Infect Dis, 2021, 72(Suppl 2): S79-S88.
[14] Koehler P, Bassetti M, Chakrabarti A, et al. Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance[J]. Lancet Infect Dis, 2021, 21(6): e149-e162.
[15] Gandhi MK, Khanna R. Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments[J]. Lancet Infect Dis, 2004, 4(12): 725-738.
[16] Orenstein JM, Dieterich DT. The histopathology of 103 consecutive colonoscopy biopsies from 82 symptomatic patients with acquired immunodeficiency syndrome: original and look-back diagnoses[J]. Arch Pathol Lab Med, 2001, 125(8): 1042-1046.
[17] He J, Liu Y, Wang Z, et al. Colonoscopy in the diagnosis of intestinal graft versus host disease and cytomegalovirus enteritis following allogeneic haematopoietic stem cell transplantation[J]. Chin Med J(Engl), 2008, 121(14): 1285-1289.
[18] Wetwittayakhlang P, Rujeerapaiboon N, Wetwittayakhlung P, et al. Clinical features, endoscopic findings, and predictive factors for mortality in tissue-invasive gastrointestinal cytomegalovirus disease between immunocompetent and immunocompromised patients[J]. Gastroenterol Res Pract, 2021, 2021: 8886525. doi: 10.1155/2021/8886525.
[19] Razonable RR, Humar A. Cytomegalovirus in solid organ transplant recipients—Guidelines of the American Society of Transplantation Infectious Diseases Community of Practice[J]. Clin Transplant, 2019, 33(9): e13512. doi: 10.1111/ctr.13512.
[20] Yeh PJ, Wu RC, Chen CL, et al. Cytomegalovirus diseases of the gastrointestinal tract in immunocompetent patients: a narrative review[J]. Viruses, 2024, 16(3): 346. doi: 10.3390/v16030346.
[21] Kreitmann L, Helms J, Martin-Loeches I, et al. ICU-acquired infections in immunocompromised patients[J]. Intensive Care Med, 2024, 50(3): 332-349.
[22] Gatto I, Biagioni E, Coloretti I, et al. Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality[J]. Intensive Care Med, 2022, 48(6): 706-713.
[23] Cevik M, Tate M, Lloyd O, et al. SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis[J]. Lancet Microbe, 2021, 2(1): e13-e22.
[24] Lindahl AL, Ahava MJ, Haukipää M, et al. Successful treatment of persisting SARS-CoV-2 infection in an immunocompromised patient with repeated nirmatrelvir/ritonavir courses: a case report[J]. Infect Dis(Lond), 2023, 55(8): 585-589.
[25] Chan M, Linn MMN, OHagan T, et al. Persistent SARS-CoV-2 PCR positivity despite anti-viral treatment in immunodeficient patients[J]. Lancet Infect Dis, 2023, 43(6): 1083-1092.
[26] Machkovech HM, Hahn AM, Garonzik Wang J, et al. Persistent SARS-CoV-2 infection: significance and implications[J]. Lancet Infect Dis, 2024, 24(7): e453-e462.
[27] 骆琼珍, 徐文帅, 高博, 等.新型冠状病毒感染患者核酸长期阳性的相关因素与核酸转阴的特点分析[J]. 中华医学杂志,2024, 104(5): 385-388. LUO Qiongzhen, XU Wenshuai, GAO Bo, et al. Analysis of the correlative factors of long-term positive nucleic acid and the characteristics of nucleic acid conversion in novel coronavirus infected patients[J]. National Medical Journal of China, 2024, 104(5): 385-388.
[28] Peluso MJ, Deveau TM, Munter SE, et al. Chronic viral coinfections differentially affect the likelihood of developing long COVID[J]. J Clin Invest, 133(3): e163669. doi: 10.1172/JCI163669.
[1] 李波波 李道堂 刘曙光 王兴武. 食管癌患者血清中DKK-1的表达[J]. 山东大学学报(医学版), 2209, 47(6): 58-61.
[2] 徐平 于国放 李霞. 不同类型甲状腺上动脉PSV对Graves病与桥本氏甲状腺炎鉴别诊断的价值[J]. 山东大学学报(医学版), 2209, 47(6): 62-64.
[3] 王欣,邢春燕,杨艳平. 血清磷酸丙酮酸水合酶检测对诊断侵袭性白念珠菌感染的临床价值[J]. 山东大学学报(医学版), 2209, 47(6): 92-94.
[4] 巩性军,吴树明,张供,李守先,庞昕焱. 无顶冠状静脉窦综合征的诊断和外科治疗[J]. 山东大学学报(医学版), 2209, 47(6): 129-.
[5] 孙丛丛,崔文静,张锦涛,张东,刘晓菲,潘云,亓倩,徐嘉蔚,曾荣,郭红喜,董亮. 铁死亡在支气管哮喘气道重塑中的作用[J]. 山东大学学报 (医学版), 2024, 62(7): 1-9.
[6] 宋艳艳,左淑英. 透明细胞肾细胞癌颌下腺转移1例并文献复习[J]. 山东大学学报 (医学版), 2024, 62(7): 120-124.
[7] 王凤燕,梁振宇,李雪萍,陈荣昌. 慢性阻塞性肺疾病近年临床研究热点[J]. 山东大学学报 (医学版), 2024, 62(5): 7-15.
[8] 丁伊人,刘婉莹,姚蕾,姚欣. 大环内酯类抗生素治疗哮喘的研究进展[J]. 山东大学学报 (医学版), 2024, 62(5): 21-27.
[9] 王莉莎,王上增,史栋梁,张仲博,任博文,王云飞,郭中华,周晓宁. 乌头汤对膝骨关节炎大鼠模型的治疗作用[J]. 山东大学学报 (医学版), 2024, 62(5): 64-71.
[10] 冯绪梅,宋相庆,季冠虹,赵小刚,肖兆华. 血浆外泌体miR-548k在食管鳞癌中的表达及诊断价值[J]. 山东大学学报 (医学版), 2024, 62(5): 79-88.
[11] 杨浩然,刘青,徐力群,张盼盼,姜涛. 应用引导组织再生术及植骨术治疗种植体周围炎1例[J]. 山东大学学报 (医学版), 2024, 62(4): 101-107.
[12] 芦兰,曾放平,唐斯晗,于晓黎,韩明勇. 光动力治疗老年眼睑皮肤基底细胞癌1例[J]. 山东大学学报 (医学版), 2024, 62(3): 117-120.
[13] 刘粉,曾荣,李慧梅,董亮. 遗传性蛋白S缺乏症所致肺栓塞1例[J]. 山东大学学报 (医学版), 2024, 62(1): 111-114.
[14] 宋兆录,董正璇,彭传真,黄彩娜,胡克清,黄永胜,阎磊. 肾透明细胞癌中预后相关RNA编辑位点的筛选[J]. 山东大学学报 (医学版), 2023, 61(9): 69-78.
[15] 于婷,李媛,吴梅. 超声诊断羊膜带综合征并胎头离断1例[J]. 山东大学学报 (医学版), 2023, 61(8): 122-124.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] 李新钢,张鑫,陈安静. 当代脑计划研究进展[J]. 山东大学学报 (医学版), 2020, 1(8): 5 -9, 21 .
[2] 索东阳,申飞,郭皓,刘力畅,杨惠敏,杨向东. Tim-3在药物性急性肾损伤动物模型中的表达及作用机制[J]. 山东大学学报 (医学版), 2020, 1(7): 1 -6 .
[3] 丁祥云,于清梅,张文芳,庄园,郝晶. 胰岛素样生长因子II在84例多囊卵巢综合征患者颗粒细胞中的表达和促排卵结局的相关性[J]. 山东大学学报 (医学版), 2020, 1(7): 60 -66 .
[4] 黄涛,林晓英,李芳邻,钟宁,刘运芳,孟晓慧,郑玉兰,宋文延 . 促红细胞生成素对全脑缺血再灌注损伤大鼠血红素加氧酶-1表达的影响[J]. 山东大学学报(医学版), 2008, 46(3): 225 -228 .
[5] 吴强,何泽鲲,刘琚,崔晓萌,孙双,石伟. 基于机器学习的脑胶质瘤多模态影像分析[J]. 山东大学学报 (医学版), 2020, 1(8): 81 -87 .
[6] 罗昕,何兵,聂清生,侯震波,董军,李玉花,曾祥芹,刘伟,孔德民,曹金凤. 磁共振扩散加权成像单指数模型与扩散峰度成像模型在61例肾透明细胞癌分级中的对比[J]. 山东大学学报 (医学版), 2020, 1(7): 89 -95 .
[7] 王会,程莲,徐淑军. 内镜下两种入路232例垂体瘤切除术对嗅觉功能影响的临床观察[J]. 山东大学学报 (医学版), 2020, 1(8): 95 -100 .
[8] 徐继禧,陈伟健. 髓内弥漫性中线胶质瘤伴H3 K27M突变1例[J]. 山东大学学报 (医学版), 2020, 1(7): 96 -101 .
[9] 王剑,周文婧,薛知易,刘晓菲. 脑胶质母细胞瘤模型研究概况及类脑模型的研发应用[J]. 山东大学学报 (医学版), 2020, 1(8): 74 -80 .
[10] 王东盛,刘倩,寇妍. PDGF及其受体在大鼠胰腺纤维化中的作用[J]. 山东大学学报(医学版), 2006, 44(4): 360 -363 .