山东大学学报 (医学版) ›› 2022, Vol. 60 ›› Issue (8): 84-90.doi: 10.6040/j.issn.1671-7554.0.2021.1377
安雯1,黄刚1,于岩波2,左秀丽2,李延青2
AN Wen1, HUANG Gang1, YU Yanbo2, ZUO Xiuli2, LI Yanqing2
摘要: 目的 提高临床医生对华氏巨球蛋白血症消化道受累的认识。 方法 报告1例慢性腹泻伴体质量减轻最终诊断为华氏巨球蛋白血症病例,回顾文献讨论该病累及消化道的特点。 结果 我们报告1例华氏巨球蛋白血症明显胃肠道受累的病例,表现为慢性腹泻伴体重减轻和低蛋白血症。小肠活检淀粉样变阴性。患者接受利妥昔单抗联合苯达莫司汀治疗腹泻很快缓解。我们检索文献回顾性分析华氏巨球蛋白血症与消化道症状的关联。 结论 提高对华氏巨球蛋白血症胃肠道表现的认识可能有助于解释和治疗这种惰性、潜在危及生命的淋巴系统恶性疾病。
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