新型冠状病毒肺炎病例1 403例密切接触者发病分析

doi:10.6040/j.issn.1671-7554.0.2020.284

摘要/Abstract

摘要： 目的了解新型冠状病毒肺炎病例密切接触者的接触情况和发病情况。方法采用回顾性流行病学方法,对2020年1月23日至2月29日追踪到的1 403例新型冠状病毒病例密切接触者的接触情况和发病情况进行描述分析,并应用χ2检验进行比较分析。结果密切接触者的接触频率以偶尔接触(78.62%)为主。本地病例的密切接触者与外地病例的密切接触者的接触地点、接触方式的构成有明显差别。本地病例的密切接触者罹患率为2.37%,外地病例的密切接触者罹患率为0,总体密切接触者罹患率为1.78%。结论密切接触者发病与接触的频率、接触程度有关,共同居住生活,导致频繁接触,从而引起多起家庭聚集性发病,其罹患率显著高于其他接触情况的罹患率。落实家庭防控措施,有助于减少家庭聚集性发病。

关键词: 新型冠状病毒肺炎, 密切接触者, 罹患率

Abstract: Objective To study the exposure and incidence of close contacts of corona virus disease 2019(COVID-19)cases. Methods The retrospective epidemiological method was used to describe and analyze the contact and incidence of 1 403 close contacts from January 23 to February 29, 2020, and the comparative analysis was made using χ2 test. Results The frequency of close contacts was mainly occasional(78.62%). There was a difference in the composition of locations and ways of contact between contacts of local and nonlocal cases. The attack rate of close contacts of local cases was 2.37%, and that of nonlocal cases was 0. The mean attack rate of all close contacts was 1.78%. Conclusion The incidence of close contacts has a correlation with the frequency and degree of contact. Living together results in the frequent contact, which further leads to multiple clusters in families. The attack rate of family cluster is significantly higher than that of other contacts. Implementing family prevention and control measures will help reduce the attack rate of family cluster.

Key words: Corona virus disease 2019, Close contacts, Attack rate

中图分类号:

R181.3

周林,刘晓雪,李战,耿兴义,刘庆皆. 新型冠状病毒肺炎病例1 403例密切接触者发病分析[J]. 山东大学学报 (医学版), 2020, 58(4): 58-61.

ZHOU Lin, LIU Xiaoxue, LI Zhan, GENG Xingyi, LIU Qingjie. Incidence analysis of 1 403 close contacts of corona virus disease 2019 patients in different contact modes[J]. Journal of Shandong University (Health Sciences), 2020, 58(4): 58-61.

参考文献

[1] 截至2月22日24时新型冠状病毒肺炎疫情最新情况[EB/OL].(2020-02-23)[2020-02-23]. http://www. nhc.gov.cn/xcs/yqfkdt/202002/07e5b22758364f2482d83537ef3975d2.shml.
[2] 崔亮亮, 耿兴义, 赵小冬, 等. 济南市现阶段新型冠状病毒肺炎的流行特征与思考[J]. 山东大学学报(医学版), 2020, 58(3): 52-57. CUI Liangliang, GENG Xingyi, ZHAO Xiaodong,et al. Reflection and epidemiological characteristics of coronavirus disease 2019 in Jinan City[J]. Journal of Shandong University(Health Sciences), 2020, 58(3): 52-57.
[3] 新冠疫情国际日报[EB/OL].(2020-02-23)[2020-02-23]. https://baijiahao.baidu.com/sid=16593016149-94790985&wfr= spider&for=pc.
[4] 中华人民共和国国家卫生健康委员会. 关于印发新型冠状病毒肺炎诊疗方案(试行第5版)的通知[EB/OL].(2020-02-05)[2020-03-14]. http://www.nhc.gov.cn/yzygj/s7653p/202002/3b09b894ac9b4204a79db5b8912d4440.shtml.
[5] 中华人民共和国国家卫生健康委员会. 国家卫生健康委办公厅关于印发新型冠状病毒肺炎防控方案(第4版)的通知[EB/OL].(2020-02-06)[2020-03-14]. http://www.gov.cn/zhengce/zhengceku/2020-02/07/content_5475813.htm.
[6] 李士雪, 单莹. 新型冠状病毒肺炎研究进展述评[J]. 山东大学学报(医学版), 2020, 58(3): 19-25. LI Shixue, SHAN Ying. Latest research advances on novel coronavirus pneumonia[J]. Journal of Shandong University(Health Sciences), 2020, 58(3): 19-25.
[7] 周虹, 朱韩武, 陈柏塘, 等. 湖南省郴州市Y县一起家庭聚集性新型冠状病毒肺炎疫情调查分析[J]. 上海预防医学, 2020, 32(3). doi: 10.19428/j.cnki.sjpm.2020.20078. ZHOU Hong, ZHU Hanwu, CHEN Baitang, et al. Epidemiological survey on a family aggregation COVID-19 in Y County, Chenzhou City, Hunan[J]. Shanghai Journal of Preventive Medicine, 2020, 32(3). doi: 10.19428/j.cnki.sjpm.2020.20078.
[8] 刘苗, 万曦, 涂晓燕, 等. 一起家庭聚集性儿童感染新型冠状病毒分析[J]. 武汉大学学报(医学版), 2020. https://doi.org/10.14188/j.1671-8852.2020.0078. LIU Miao, WAN Xi, TU Xiaoyan, et al. Family cluster of child SARS-CoV-2 infections: a case report [J]. Medical Journal of Wuhan University, 2020. https://doi.org/10.14188/j.1671-8852.2020.0078.
[9] 中华预防医学会新型冠状病毒肺炎防控专家组. 新型冠状病毒肺炎流行病学特征的最新认识[J]. 中国病毒病杂志, 2020, 10(2): 1-7. Special Expert Group for Control of the Epidemic of Novel Coronavirus Pneumonia of the Chinese Preventive Medicine Association. An update on the epidemiological characteristics of novel coronavirus pneumonia(COVID-19)[J]. Chinese Journal of Viral Diseases, 2020, 10(2): 1-7.
[10] 仇元营, 王松强, 王小丽, 等. 一起新型冠状病毒肺炎家庭聚集性流行病学分析[J]. 中华流行病学杂志, 2020, 41(4): 506-509. QIU Yuanying, WANG Songqiang, WANG Xiaoli, et al. Epidemiological analysis on a family cluster of COVID-19[J]. Chinese Journal of Epidemiology, 2020, 41(4): 506-509.
[11] 庞星火, 刘东磊, 龚晓红, 等. 北京市SARS患者密切接触者发病及其危险因素分析[J]. 中华流行病学杂志, 2004, 25(8): 674-676. PANG Xinghuo, LIU Donglei, GONG Xiaohong, et al. Study on the risk factors related to severe acute respiratory syndrome among close contactors in Beijing[J]. Chinese Journal of Epimemiology, 2004, 25(8): 674-676.
[12] 庞星火, 杨鹏, 李爽, 等. 北京市2009年甲型H1N1流感患者密切接触者的流行病学特点[J]. 中华结核和呼吸杂志, 2011, 34(5): 348-352. PANG Xinghuo, YANG Peng, LI Shuang, et al. Epidemiological characteristics of infection for close contacts of pandemic(H1N1)2009 in Beijing[J]. Chinese Journal of Tuberculosis and Respiratory Diseases, 2011, 34(5): 348-352.
[13] Chan JF, Yuan SF, Kok KH, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster[J]. Lancet, 2020, 395(10223): 514-523.
[14] Hellewell J, Abbott S, Gimma A, et al. Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts[J]. Lancet Glob Health, 2020, 8(4):e488-e496. doi: 10.1016/S2214-109X(20)30074-7.
[15] 高文静, 李立明. 新型冠状病毒肺炎潜伏期或隐性感染者传播研究进展[J]. 中华流行病学杂志, 2020, 41(4): 485-488. GAO Wenjing, LI Liming. Advances on presymptomatic or asymptomatic carrier transmission of COVID-19[J]. Chinese Journal of Epidemiology, 2020, 41(4): 485-488.

相关文章 15

[1]	曹义海. 血管生成在疾病治疗中的应用与展望[J]. 山东大学学报 (医学版), 2021, 59(9): 9-14.
[2]	杨璇,李岩志,马伟,贾崇奇. 基于两样本孟德尔随机化的肺功能与新型冠状病毒肺炎病死风险的因果关系[J]. 山东大学学报 (医学版), 2021, 59(7): 104-111.
[3]	周溪,黄霂晗,任玉洁,邱洋. 新型冠状病毒感染与天然免疫及炎症反应[J]. 山东大学学报 (医学版), 2021, 59(5): 15-21.
[4]	于莹,张功,刘晶,颜世童,韩涛,黄海量. 基于网络药理学和分子对接方法探析黄芪预防新型冠状病毒肺炎的潜在作用机制[J]. 山东大学学报 (医学版), 2021, 59(4): 6-16.
[5]	任敏敏,王广梅,张丽,杨瑶瑶,封丹珺. 335名抗疫一线护理人员心理弹性对共情疲劳的影响[J]. 山东大学学报 (医学版), 2021, 59(2): 88-94.
[6]	袁勇贵,李磊,沈仲夏,陈刚,吴义高,岳莹莹. 新型冠状病毒肺炎疫情下精神障碍诊疗的防控策略[J]. 山东大学学报 (医学版), 2020, 58(4): 1-6.
[7]	常彩云,于秋燕,赵小冬,王芳,李伟,阮师漫,耿兴义. 济南市首例新型冠状病毒肺炎病例及其相关家庭聚集性疫情分析[J]. 山东大学学报 (医学版), 2020, 58(4): 7-11.
[8]	杨丽,李战,刘晓雪,焦海涛,周林,刘庆皆,刘铁诚,耿兴义. 济南市新型冠状病毒肺炎密切接触者隔离医学观察情况分析与评价[J]. 山东大学学报 (医学版), 2020, 58(4): 12-16.
[9]	乔宇,崔亮亮,李帅,王峰,阮师漫,景一鸣,刘翀. 智能问答机器人系统研发及应用研究——以济南市新型冠状病毒肺炎疫情处置应对为例[J]. 山东大学学报 (医学版), 2020, 58(4): 17-22.
[10]	李新蕊,耿兴义,赵小冬,刘岚铮,王蔚茹,崔亮亮,李战,常彩云,阮师漫. 济南市47例新型冠状病毒肺炎疫情流行综合分析[J]. 山东大学学报 (医学版), 2020, 58(4): 23-27.
[11]	赵怀龙,吕燕,赵红,赵宝添,韩莹,杨国樑,王春荣,关恒云,刘辉,刘岚铮. 济南市47例新型冠状病毒肺炎患者取样部位对核酸检测结果的影响[J]. 山东大学学报 (医学版), 2020, 58(4): 28-31.
[12]	李新蕊,耿兴义,王蔚茹,赵小冬,刘岚铮,张晓菲,吕翠霞,常彩云,李战,崔亮亮,阮师漫. 37例新型冠状病毒肺炎聚集性思考[J]. 山东大学学报 (医学版), 2020, 58(4): 32-40.
[13]	杨柳,李战,许华茹,常彩云,刘仲,李传彬,孙湛,景睿,刘铁诚,耿兴义,周敬文. 济南市10例儿童新型冠状病毒肺炎确诊病例流行病学和临床特征[J]. 山东大学学报 (医学版), 2020, 58(4): 36-39.
[14]	景睿,刘铁诚,王春荣,胡艳霞,武晶晶,张文茜,耿兴义,阮师漫. 济南市某商城新型冠状病毒肺炎聚集性疫情调查[J]. 山东大学学报 (医学版), 2020, 58(4): 40-43.
[15]	赵梦娇,刘仲,李战,常彩云,赵小冬,耿兴义. 济南市一起新型冠状病毒肺炎聚集性疫情调查[J]. 山东大学学报 (医学版), 2020, 58(4): 44-48.

多维度评价

Viewed

Full text

Abstract

Cited

Shared

Discussed