Journal of Shandong University (Health Sciences) ›› 2021, Vol. 59 ›› Issue (6): 33-37.doi: 10.6040/j.issn.1671-7554.0.2021.0481

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Progress in glucocorticoid-induced osteoporosis

CHEN Shihong   

  1. Department of Endocrinology, The Second Hospital of Shandong University, Jinan 250033, Shandong, China
  • Published:2021-06-10

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Abstract: Glucocorticoids are widely used in the treatment of allergic and autoimmune diseases. Glucocorticoid-induced osteoporosis(GIOP)is one of the adverse reactions of long-term application of glucocorticoids, which is characterized by continuous decrease of bone formation accompanied by increase of bone resorption, leading to increased incidence of fracture and bringing serious harm to patients. Herein, we review the pathogenesis of GIOP and its prevention and treatment drugs, in order to raise the attention of clinicians to GIOP.

Key words: Glucocorticoids, Osteoporosis, Osteoblast, Osteoclast

CLC Number: 

  • R574
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