JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2017, Vol. 55 ›› Issue (10): 21-27.doi: 10.6040/j.issn.1671-7554.0.2017.318

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Progress in the etiology and pathogenesis of Alzheimers disease

DU Heng1, YUAN Xiaodong1,2   

  1. 1. Department of Neurology, Shandong Qianfoshan Hospital Affiliated to Shandong University, Jinan 250014, Shandong, China;
    2. Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, Shandong, China
  • Received:2017-04-12 Online:2017-10-10 Published:2017-10-10

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Abstract: Alzheimers disease(AD)is a neurodegenerative disease majorly attacking aging population. AD is the most common type of aging-related dementia, featured by irreversible cognitive impairments and loss of social function. The 山 东 大 学 学 报 (医 学 版)55卷10期 -杜蘅,等.阿尔茨海默病病因及发病机制研究进展 \=-etiology and pathogenesis of AD have not been fully elucidated yet, which significantly deters the development of strategies for AD prevention and treatment. Here, in summary of the up-to-date research progress, we reviewed the risk factors for AD as well as the mechanisms of the pathogenesis of this neurological disorder.

Key words: Etiology, Pathogenesis, Alzheimers disease, Dementia, Risk factors

CLC Number: 

  • R741.02
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