JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2017, Vol. 55 ›› Issue (2): 38-44.doi: 10.6040/j.issn.1671-7554.0.2016.1350

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CT-guided 125I seed brachytherapy for superficial lymph node metastases: a report of 23 cases

LIN Qi, ZHANG Ying, DAI Jianjian, XU Ruicai, YANG Qi, GENG Baocheng, HAN Mingyong   

  1. Department of Health Oncology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250014, Shandong, China
  • Received:2016-10-20 Online:2017-02-10 Published:2017-02-10

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Abstract: Objective To evaluate the efficacy and complications of CT-guided permanent 125I seed brachytherapy in patients with the superficial lymph node metastases. Methods Clinical data of 23 patients with 28 superficial lymph node metastases who underwent CT-guided 125I seed brachytherapy during Dec. 2014 and Jun. 2016 were retrospectively reviewed. Brachytherapy was preplanned for all patients using a 3-dimensional radiation therapy planning system. With CT guidance, 125I seed was placed into the metastases. Dosimetry verification was performed immediately after operation. Efficacy and complications were evaluated 1, 3, 6, 9 and 12 months postoperatively. Results The median local control rate of 1, 3, 6, 9 and 12 months was 84.6%, 82.4%, 81.2%, 83.3% and 85.7%, respectively. The median follow-up was 9 months(1-16 months), during which 8 patients died and 15 survived. The local control time was 12 months(95% CI: 7.4, 16.5), the median progression-free-survival(PFS)was 3 months(95% CI: 0.3, 5.7), P=0.194. No major complications occurred during or after brachytherapy except for Ⅰ/Ⅱ acute skin radioreaction in 6 cases. Conclusion CT-guided 125I seed brachytherapy is a safe and effective treatment for superficial lymph node metastases with few complications.

Key words: Complications, Local control rate, Superficial lymph node metastases, 125I seed

CLC Number: 

  • R730.5
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