JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2017, Vol. 55 ›› Issue (2): 8-13.doi: 10.6040/j.issn.1671-7554.0.2016.1477

Previous Articles     Next Articles

Prevention and treatment of complications of abdominal tumor by radioactive seeds implantation

WANG Juan, ZHANG Hongtao, GAO Zhen, DI Xuemin, WANG Zeyang   

  1. Department of Oncology, Hebei General Hospital, Hebei Provincial Radioactive Seed Brachytherapy Center;
    Hebei Provincial Radioactive Seed Brachytherapy Research Institution, Shijiazhuang 050051, Hebei, China)〓山〓东〓大〓学〓学〓报〓(医〓学〓版)55卷2期〓-王娟, 等.腹部肿瘤放射性粒子植入并发症处理及预防〓\=-〓〓
  • Received:2016-11-09 Online:2017-02-10 Published:2017-02-10

PDF (PC)

777

Abstract: Abdominal malignant tumors such as liver cancer, gastric cancer, pancreatic cancer and colorectal cancer have high morbidity and mortality due to easy recurrence and metastasis but hard resection. Most of them are already advanced once detected. Whats more, some tumors are resistant to chemotherapy. Targeted medicine therapy can improve the prognosis to a certain extent, but it will inevitably lead to resistance. Radioactive seeds are a new and effective method for patients with advanced malignant tumors because it is highly conformal, durable and safe. Besides, it can accurately locate the tumor. However, the mechanism and prevention of complications still need to be explored, such as common complications including gastrointestinal reaction, infection, bleeding, ulcers, and life-threatening complications including bleeding and pulmonary embolism. Great attention should be paid to the management of these complications.

Key words: Complications, Radioactive seeds, Abdominal tumor

CLC Number: 

  • R711
[1] Yao L, Jiang Y, Jiang P, et al. CT-guided permanent 125I seed interstitial brachytherapy for recurrent retroperitoneal lymph node metastases after external beam radiotherapy[J]. Brachytherapy, 2015, 14(5): 662-669.
[2] 姚红响, 陈根生, 徐磊, 等. CT引导下同轴法125I粒子植入治疗腹膜后淋巴结转移瘤21例[J]. 介入放射学杂志, 2014, 23(1): 42-45. YAO Hongxiang, CHEN Gensheng, XU Lei, et al. CT-guide coaxial 125I seeds implantation for the treatment of retroperltoneal lymph node metastasis: analysis of 21 cases[J]. Journal of Interventional Radiology, 2014, 23(1): 42-45.
[3] 郭金友, 郑家平, 费伦, 等. CT引导下125I粒子植入治疗合并癌痛难治性恶性肿瘤[J]. 介入放射学杂志, 2016, 25(2): 141-144. GUO Jinyou, ZHENG Jiaping, FEI Lun, et al. CT-guided 125I seed implantation for the treatment of refractory malignant tumor accompanied with cancerous pain[J]. Journal of Interventional Radiology, 2016, 25(2): 141-144.
[4] 吴娟, 隋爱霞, 张宏涛, 等. CT引导下125I粒子治疗腹膜后恶性肿瘤穿刺路径分析[J]. 介入放射学杂志, 2015, 24(10): 902-905. WU Juan, SUI Aixia, ZHANG Hongtao, et al. CT-guided 125I seed implantation for the treatment of retroperitoneal malignant tumors: analysis of puncturing approaches[J]. Journal of Interventional Radiology, 2015, 24(10): 902-905.
[5] Huang MW, Liu SM, Zheng L, et al. A digital model individual template and CT-guided 125I Seed implants for malignant tumors of the head and neck[J]. J Radiat Res, 2012, 53(6): 973-977.
[6] Lin L, Wang J, Jiang Y, et al. Interstitial 125I seed implantation for cervical lymph node recurrence after multimodal treatment of thoracic esophageal squamous cell carcinoma[J]. Technol Cancer Res Treat, 2015, 14(2): 201-207.
[7] Gao F, Li C, Gu Y, et al. CT-guided 125I brachytherapy for mediastinal metastatic lymph nodes recurrence from esophageal carcinoma: effectiveness and safety in 16 patients[J]. Eur J Radiol, 2013, 82(2): 70-75.
[8] Wu LL, Luo JJ, Yan ZP, et al. Comparative study of portal vein stent and TACE combined therapy with or without endovascular implantation of iodine-125 seeds strand for treating patients with hepatocellular carcinoma and main portal vein tumor thrombus[J]. Zhonghua Gan Zang Bing Za Zhi, 2012, 20(12): 915-919.
[9] 易福梅, 王皓, 袁慧书, 等. CT引导125I放射性粒子植入治疗局部复发性直肠癌的疗效分析[J]. 中华放射医学与防护杂志, 2014, 34(1): 30-33. YI Fumei, WANG Hao, YUAN Huishu, et al. CT-guided 125I radioactive seed implantation for locally recurrent rectal cancer[J]. Chinese Journal of Radiological Medicine and Protection, 2014, 34(1): 30-33.
[10] Yoshida K, Ohashi T, Yorozu A, et al. Comparison of preplanning and intraoperative planning for 125I prostate brachytherapy[J]. Jpn J Clin Oncol, 2013, 43(4): 383-389.
[11] 何闯, 刘云, 杨丽, 等. CT引导下125I粒子治疗腹膜后淋巴结转移瘤植入技巧[J]. 介入放射学杂志, 2015, 24(6): 534-536. HE Chuang, LIU Yun, YANG Li, et al. CT- guided 125I seed implantation for retroperitoneal lymph node metastases: its technical points[J]. Journal of Interventional Radiology, 2015, 24(6): 534-536.
[12] 俞炎平, 江海涛, 姚征, 等. CT引导下经皮胰腺穿刺活检和组织间植入治疗的径路及安全性[J]. 中华肿瘤杂志, 2013, 35(8): 608-612. YU Yanping, JIANG Haitao, YAO Zheng, et al. Feasibility and safety of CT-guided percutaneous needle biopsy and subsequent iodine-125 seed interstitial implantation for pancreatic cancer[J]. Chinese Journal of Oncology, 2013, 35(8): 608-612.
[13] Li WH, Dai ZY, Wan HG, et al. Endovascular implantation of iodine-125 seeds strand and portal vein stenting followed by transcatheter arterial chemoembolization combined therapy with sorafenib for hepatocellular carcinoma with main portal vein tumor thrombus[J]. Zhonghua Yi Xue Za Zhi, 2016, 96(23): 1838-1842.
[14] 郑家平, 邵国良, 罗君, 等. CT引导下125I粒子组织间植入治疗难治性肝癌[J]. 介入放射学杂志, 2015, 24(3): 260-264. ZHENG Jiaping, SHAO Guoliang, LUO Jun, et al. CT-guided 125I seeds interstitial implantation for the refractory liver cancers ineffective to commonly used therapies[J]. Journal of Interventional Radiology, 2015, 24(3): 260-264.
[15] 刘健, 张福君, 吴沛宏, 等. CT导向下125I粒子植入治疗肝门区肝癌[J]. 介入放射学杂志, 2005, 14(6): 606-609. LIU Jian, ZHANG Fujun, WU Peihong, et al. CT-guided radioactive seed 125I implantation in treating hilar hepatic tumor and metastatic lymph nodes[J]. Journal of Interventional Radiology, 2005, 14(6): 606-609.
[16] 姜涛,王大光,王国良,等.泌尿系恶性肿瘤患者手术联合 DC-CIK免疫细胞治疗安全性临床研究[J].中华临床医师杂志,2015, 9(12): 2327-2330. JIANG Tao, WANG Daguang, WANG Guoliang, et al. Security of clinical research in urological cancer patients after surgery combined DC-CIK cells immunotherapy treatment[J]. Journal of Clinical Physicians, 2015, 9(12): 2327-2330.
[17] 郭宝明, 张治民. 胃镜下植入放射性碘-125粒子治疗晚期胃癌的疗效及安全性[J].现代中西医结合杂志, 2014, 23(27): 3004-3007.
[18] 王娟, 隋爱霞, 赵静, 等. CT引导下经胃入路125I粒子治疗腹膜后转移癌10例[J]. 介入放射学杂志, 2015, 24(8): 698-701. WANG Juan, SUI Aixia, ZHAO Jing, et al. CT guided 125I brachytherapy via transgastric approach for the treatment of retroperitoneal metastases: initial experience in 10 cases[J]. Journal of Interventional Radiology, 2015, 24(8): 698-701.
[19] 王娟. 腹部肿瘤放射性粒子治疗技术[M]. 北京: 人民卫生出版社, 2014.
[20] Liu B, ZHhou T, Geng J, et al. Percutaneous computed tomography-guided iodine-125 seeds implantation for unresectable pancreas[J]. Indian J Cancer, 2015, 52(2): 69-74.
[21] Liu K, Ji B, Zhang W, et al. Comparison of iodine-125 seed implantation and pancreaticoduodenectomy in the treatment of pancreatic cancer[J]. Int J Med Sci, 2014, 11(9): 893-896.
[22] 李会星, 史宪杰, 梁雨荣, 等. 125I粒子植入治疗晚期胰腺癌术后胰瘘的危险因素[J]. 中华肝胆外科杂志, 2014, 20(12): 862-865. LI Huixing, SHI Xianjie, LIANG Yurong, et al. Risk factors of pancreatic fistula after 125I particles implantation for advanced pancreatic carcinoma[J]. Chinese Journal of Hepatobiliary Surgery, 2014, 20(12): 862-865.
[23] Kawai M, Hirono S, Okada K, et al. Randomized controlled trial of pancreaticojejunostomy versus stapler closure of the pancreatic stump during distal pancreatectomy to reduce pancreatic fistula[J]. Ann Surg, 2016, 264(1): 180-187.
[24] 杜义安, 俞炎平, 王实, 等. 内镜联合125I粒子植入在老年胰腺癌患者手术治疗中的应用[J]. 中华老年医学杂志, 2013, 32(4): 390-392. DU Yian, YU Yanping, WANG Shi, et al. Application of endoscopy combined with 125I seed implantation in the pancreatic cancer surgery in elderly patients[J].Chinese Journal of Geriatrics, 2013, 32(4): 390-392.
[25] 于聪慧, 姚军波, 杨荣华, 等. 125I放射性粒子植入治疗晚期胰腺癌26例临床分析[J]. 国际外科学杂志, 2014, 41(9): 614-617. YU Conghui, YAO Junbo, YANG Ronghua, et al. Clinical analysis of 125I radioactive seeds implantation treatment in 26 cases of advanced pancreatic cancer[J]. International Journal of Surgery, 2014, 41(9): 614-617.
[26] 杨军, 关秀文, 韦炳邓, 等. 胃癌根治术后胃瘫综合征的治疗及危险因素分析[J]. 中国现代普通外科进展, 2012, 15(7): 578-579.
[27] 王俊杰, 修典荣, 冉维强, 等. 术中超声引导放射性125I粒子组织间植入治疗胰腺癌[J].中华放射肿瘤学杂志, 2007, 16(1): 34-37. WANG Junjie, XIU Dianrong, RAN Weiqiang, et al. Intraoperative ultrasound guided iodine-125 seed implantation for unresectable pancreatic carcinoma[J]. Chinese Journal of Radiation Oncology, 2007, 16(1): 34-37.
[28] 黄洪军, 江勇, 吴宝强, 等. 术中125I放射性粒子植入治疗不能切除晚期胰腺癌的并发症和预后分析[J]. 肝胆胰外科杂志, 2014, 26(4): 281-284. HUANG Hongjun, JIANG Yong, WU Baoqing, et al. Complications and prognosis of intraoperative iodine-125 seed implantation therapy in patients with unresectable advanced pancreatic cancer[J]. Journal of Hepatopancreatobiliary Surgery, 2014, 26(4): 281-284.
[29] 沈新颖, 张彦舫, 窦永充, 等. 125I粒子 CT导向植入治疗恶性肿瘤多发腹膜后淋巴结转移[J]. 放射学实践, 2012, 27(10): 1128-1131. SHEN Xinying, ZHANG Yanfang, DOU Yongchong, et al. CT-guided 125I seeds implantation for the treatment of multiple retroperitoneal lymph node metastases of malignant neoplasm[J]. Radiologic Practice, 2012, 27(10): 1128-1131.
[30] 姚波, 王雅棣, 路娜, 等. 局部复发直肠癌超常规大分割同步放化疗疗效分析[J]. 中华放射医学与防护杂志, 2015, 35(8): 603-607. YAO Bo, WANG Yali, LU Na, et al. Outcomes for patients with locally recurrent rectal cancer treated with hypofractionated chemoradiotherapy without resection[J]. Chinese Journal of Radiological Medicine and Protection, 2015, 35(8): 603-607.
[1] GUO Zhihua, ZHAO Daqing, XING Yuan, WANG Wei, LIANG Leping, YANG Jing, ZHAO Qianqian. Single-stage end-to-end anastomosis in the management of severe cervical tracheal stenosis [J]. Journal of Shandong University (Health Sciences), 2020, 1(7): 72-76.
[2] ZENG Yiming, LIN Yanping. Implantation of 125I seeds for treatment of local bronchogenic carcinoma [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(4): 1-6.
[3] LU Ye, CUI Huifang, CHEN Xujun, HUANG Yihua, WU Yiqun, HUANG Jianlong, CHEN Huimin, XIONG Xianjun, CHEN Minghong. Application progress of freezing technology in intervention treatment of respiratory disease and preventive treatment for the correlated complications [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(4): 19-22.
[4] HUO Bin, WANG Lei, WANG Haitao, HUO Xiaodong, CAO Qiang, WANG Lili, ZANG Li, WANG Jinhuan, ZHENG Guanjun, CHAI Shude. Feasibility of radioactive seed implantation in the treatment of lung cancer assisted by template combined with rib drilling technique [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(2): 26-31.
[5] LIN Qi, ZHANG Ying, DAI Jianjian, XU Ruicai, YANG Qi, GENG Baocheng, HAN Mingyong. CT-guided 125I seed brachytherapy for superficial lymph node metastases: a report of 23 cases [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(2): 38-44.
[6] HAN Mingyong, HUO Bin, ZHANG Ying, LIN Qi, DAI Jianjian, XU Ruicai, YANG Qi, GENG Baocheng, ZHENG Guangjun, WANG Haitao, HUO Xiaodong, CHEN Baoming(Reviewed by CHAI Shude, WANG Junjie), 山, 东, 大, 学, 学, 报, (医, 学, 版)55卷2期, -韩明勇,等.CT联合模板引导放射性粒子植入治疗肺癌技术流程, \=-. Technical procedure of template combined with CT-guided radioactive seeds implantation for lung cancer [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(2): 14-20.
[7] LI Yang, HE Chuang, CHEN Yuxiao, YANG Li, LI Liangshan, LI Tingyuan, HUANG Xuequan. CT-guided interstitia 125I seed implantation in the treatment of long bone metastasis: a primary clinic study [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(2): 50-54.
[8] LIANG Fei, ZHANG Wenlong, ZHANG Jun, XU Chongen, ZOU Chengwei. Relevant factors and early complications of significantly elevated enzymes after off-pump coronary artery bypass grafting [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(10): 71-75.
[9] FANG Feifei, ZHANG Ying, LIN Qi, YUAN Yuan, DAI Jianjian, XU Ruicai, GENG Baocheng, HAN Mingyong. Clinical efficacy of CT-guided 125I seed brachytherapy in the treatment of metastatic hepatic carcinoma [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(12): 53-57.
[10] ZHAO Heng, YIN Qingfeng, LIU Wenguang, LIU Shenghou, XIAO Shipeng, WANG Shaojin. Application of a novel barbed suture in wound closure of hip and knee replacement [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2015, 53(8): 53-56.
[11] HU Liang， YI Yong-xiang， DING Hai， HAN Jian-bo, LIU Tao, ZHAO Liang. Relevant factors of postoperative complications for hepatectomy combined with splenectomy [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2013, 51(1): 64-66.
[12] LI Zhen-zuo1,2， ZHANG Yan3， MA Chi-cheng4， LIU Jin-bo1， SUN Yu1， HOU Xin-guo1， CHEN Li1. Association of serum vaspin with carotid plaque in new type 2 diabetic patients [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2011, 49(10): 79-.
[13] ZHAO Lijian, HAN Bo, ZHANG Jianjun, ZHUANG Jianxin, JIN Youpeng, WANG Yulin. Evaluation of transcatheter closure in 90 cases ofcongenital ventricular septal defect [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2010, 48(5): 89-92.
[14] . Posterior chamber implantable contact lens for 18 cases of high myopia [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2009, 47(10): 134-138.
[15] XI Jie, WU Shuming, PANG Xinyan, et al. Perioperative application of intraaortic balloon pump in critical patients with coronary disease [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2009, 47(01): 82-84.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Copyright 2018 © Editorial office of Journal of Shandong University (Health Sciences)
Supported by Beijing Magtech Co.Ltd