JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2014, Vol. 52 ›› Issue (12): 94-98.doi: 10.6040/j.issn.1671-7554.0.2014.494

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Application value of spectral CT imaging in differential diagnosis of hepatocellular carcinoma and hepatic mass-type cholangiocarcinoma

LIU Changxu1, ZHANG Chengqi2, WANG Xinyi2, YANG Zhiqiang2   

  1. 1. Taishan Medical University, Taian 271000, Shandong, China;
    2. Department of Medical Imaging, Qianfoshan Hospital Affiliated to Shandong University, Jinan 250014, Shandong, China
  • Received:2014-07-28 Revised:2014-11-24 Published:2014-12-10

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Abstract: Objective To explore the application value of spectral CT imaging in the differential diagnosis of hepatocellular carcinoma and hepatic mass-type cholangiocarcinoma. Methods A total of 34 liver cancer cases, including 20 hepatocellular carcinoma and 14 hepatic mass-type cholangiocarcinoma, underwent spectral CT scan. Iodine concentration, water concentration and 101 sets of monochromatic images were generated with gemstone spectral imaging post-processing software. The iodine concentration, water concentration, spectrum energy curve and normalized iodine concentration were measured at the monochromatic energy 55 Kev. The results were analyzed with independent samples t test. Results In hepatocellular carcinoma, the iodine concentration, spectrum energy curve and normalized iodine concentration were (12.84±2.38), (1.58±0.24) and (0.15±0.05) μg/cm3; while in cholangiocarcinoma, those were (10.71±3.01), (1.34±0.32) and (0.12±0.34) μg/cm3. There were significant differences between those indexes (P<0.05). The water concentration in hepatocellular carcinoma and cholangiocarcinoma were (1 041.05±6.47) and (1038.74±8.54) mg/cm3, respectively, exhibiting no significant difference (P>0.05). Conclusion Spectral CT is helpful for the differential diagnosis of hepatocellular carcinoma and hepatic mass-type cholangiocarcinoma.

Key words: Liver cancer, Tomography, Spectral CT imaging

CLC Number: 

  • R735.7
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