Journal of Shandong University (Health Sciences) ›› 2018, Vol. 56 ›› Issue (12): 73-78.doi: 10.6040/j.issn.1671-7554.0.2018.280

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Fat-containing ganglioneuroma: imaging features and clinicopathological correlation

ZHANG Lihong1, LI Xian2, WANG Linsheng2, LI Honglei3, LI Lei4   

  1. 1. Medical Imaging Center, First Peoples Hospital of Jining, Jining 272013, Shandong, China;
    2. Medical Imaging Center, Affiliated Hospital of Jining Medical University, Jining 272029, Shandong, China;
    3. CT Department, Central Hospital of Zaozhuang Mining Group, Zaozhuang 277000, Shandong, China;
    4. Department of Pathology, Affiliated Hospital of Jining Medical University, Jining 272029, Shandong, China
  • Published:2022-09-27

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Abstract: Objective To summarize the imaging features of fat-containing ganglioneuroma(FCG). Methods The imaging manifestations of 9 cases of FCG confirmed pathologically were reviewed. All cases received unenhanced and enhanced CT scanning, 4 of whom underwent unenhanced and enhanced MRI scanning. Results The ganglioneuromas were singular in all of the 9 cases, including 4 in the posterior mediastinum, 4 in the retroperitonium and 1 in the right adrenal gland. They all presented well-defined fat-containing heterogeneous masses on unenhanced CT images, and the CT values of fatty portion ranged from -120.7 to -43.4 HU. The fat was focalized around the mass in 6 cases, and diffused as patches or nodules in the other 3 cases. The intratumoral fat was verified by fat-suppressed T1WI and/or T2WI. The neural portions presenting soft-tissue density showed slightly low signals on T1WI and slightly high signals on T2WI, 山 东 大 学 学 报 (医 学 版)56卷12期 -张丽红,等.含脂肪节细胞神经瘤的影像学表现与病理对照 \=-which were slightly(n=5), moderately(n=2), and obviously(n=2)enhanced on enhanced CT, and slightly(n=3)and obviously(n=1)enhanced on enhanced MRI. All of the abdominal masses presented gradual enhancement on enhanced triphase CT and/or MRI scan. Conclusion Fat rarely occurs in ganglioneuromas. CT measurement and fat-suppression sequence of MRI can confirm its occurrence. CT and/or enhanced MRI scanning of the predilection location help to improve the diagnosis of FCG.

Key words: Fat, Ganglioneuroma, Magnetic resonance imaging, Tomography, X-ray computer

CLC Number: 

  • R814.4
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