JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES)

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18F-FDG PET-CT for lymph node staging in non-small cell lung cancer

ZHANG Cheng-qi1,WANG Guang-li2,SONG Ji-qing2,YAO Shu-zhan2,LIU Qing-wei2,CHE Jing2   

  1. 1. Department of Radiology, Shandong Qianfoshan Hospital;2. Department of Radiology, Shandong Provincial Hospital, Jinan 250021, Shandong, China
  • Received:2007-04-09 Revised:1900-01-01 Online:2007-10-24 Published:2007-10-24
  • Contact: ZHANG Cheng-qi

Abstract: Objective: To investigate the clinical value of 18F-FDG PET-CT for non-small cell lung cancer in lymph node staging. Methods:18F-FDG PET-CT (Discovery LS PET-CT in Department of Radiology of Shandong Provincial Hospital) images of 79 patients who had undergone surgeries for histopathologically proved non-small cell lung cancers without distant metastases were analyzed. PET-CT results were compared with the CT data. Findings of both modalities were compared with pathological results and were statistically analyzed. Results: There were 268 lymph node metastases in 79 patients. The sensibility, specificity and accuracy of PET-CT and CT for detecting lymphoid node metastasis were 82.84%, 96.70% and 89.83% and 58.58%, 72.89% and 65.80%, respectively. The former was obviously better than the latter. Overall tumor stage was correctly classified as N stage with CT in 58 patients and with PET-CT in 73 patients. Differences in the accuracy of lymphoid node staging between PET-CT and CT were significant (χ2=10.05, P<0.01). Conclusion: PET-CT is a very effective imaging modality for lymph node staging of nonsmall cell lung cancer.

Key words: Lung neoplasms, Tomography, emission-computed, Tomography, X-ray computed, Diagnosis, Neoplasm staging

CLC Number: 

  • R817.4
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