Journal of Shandong University (Health Sciences) ›› 2023, Vol. 61 ›› Issue (1): 100-105.doi: 10.6040/j.issn.1671-7554.0.2022.1031

• 公共卫生与管理学 • Previous Articles    

Immediate antiretroviral treatment in 1,926 cases of HIV infection through homosexual transmission in Shandong Province

WANG Jiongjiong1,2, WANG Guoyong3,4, ZHU Xiaoyan3,4, LI Ling3,4, ZHANG Na3,4, LIU Yunxia1,2,4   

  1. 1. Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, Shandong, China;
    2. Institute for Medical Dataology, Shandong University, Jinan 250002, Shandong, China;
    3. Center for AIDS/STD Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, Shandong, China;
    4. Institute of Preventive Medicine, Shandong University, Jinan 250014, Shandong, China
  • Published:2023-01-10

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Abstract: Objective To explore the influencing factors of immediate antiretroviral therapy(ART)among newly diagnosed cases of HIV infection through homosexual transmission in Shandong Province, so as to provide reference for the control of HIV transmission. Methods A total of 1,926 cases of HIV infection through homosexual transmission in 2018 were selected as the research objects. Related data were collected with retrospective cohort study. The influencing factors of immediate ART were determined with binary Logistic regression. Results The median baseline age at diagnosis was 31.15 years, the diagnostic CD4 cell level at baseline was 364 cells/μL, and the rate of immediate ART was 73.94%. Those with household registration outside Shandong had lower rate of immediate ART than those in the province(OR=0.59, 95%CI: 0.40-0.87). The detained population had lower immediate ART rate than the key population(OR=0.25, 95%CI: 0.11-0.59). Patients with baseline CD4 cell level of 351-499 and ≥500 cells/μL had lower immediate ART rate than those with ≤350 cells/μL(OR=0.71, 95%CI: 0.53-0.96; OR=0.50, 95%CI: 0.38-0.66). Conclusion It is necessary to improve the immediate ART rate among newly diagnosed cases of HIV infection through homosexual transmission in Shandong Province. In particular, to control the spread of HIV, due attention should be paid to those with household registration outside the province, the detained population and those with high baseline CD4 cell level.

Key words: Acquired immunodeficiency syndrome, Immediate antiretroviral therapy, Influencing factors, Homosexual transmission, Shandong Province

CLC Number: 

  • R512.91
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