Journal of Shandong University (Health Sciences) ›› 2018, Vol. 56 ›› Issue (11): 91-97.doi: 10.6040/j.issn.1671-7554.0.2017.1206

Previous Articles    

Association between ambient ozone and mortality of respiratory diseases in Jinan, China: a time series analysis

CAO Ruoming1, CUI Liangliang2, JIANG Chao3, JING Yiming1, ZHOU Lin4, ZHANG Lin3, LIU Shouqin1   

  1. 1. Office of Public Health Services, Jinan Municipal Center for Disease Control and Prevention, Jinan 250021, Shandong, China;
    2. Department of Environmental Health, Jinan Municipal Center for Disease Control and Prevention, Jinan 250021, Shandong, China;
    3. Shizhong District Center for Disease Control and Prevention, Jinan 250022, Shandong, China;
    4. Non-Communicable Chronic Disease Branch, Jinan Municipal Center for Disease Control and Prevention, Jinan 250021, Shandong, China
  • Published:2022-09-27

PDF (PC)

9

Abstract: Objective To investigate the association between ambient ozone(O3)and mortality of respiratory diseases in Jinan City. Methods The daily information of air pollutants, meteorological indicators and mortality of respiratory diseases during 2013 and 2015 was collected. The association between daily O3 and mortality of respiratory diseases was evaluated with general linear model(GLM)based on Quasi-Poisson regression. Confounding factors of the seasonal 山 东 大 学 学 报 (医 学 版)56卷11期 -曹若明,等.济南市大气污染物O3与居民呼吸系统疾病死亡风险的时间序列分析 \=-patterns, long-term trends, meteorological factors, day of the week(DOW)effect, holiday effect and warm-heating effect were controlled. Excess risk(ER)and 95% confidence interval(95%CI)of the mortality of respiratory diseases were calculated based on a 10 μg/m3 increase in O3 concentration. Sensitive analysis was conducted, including dual-pollutant model(O3+PM2.5, O3+SO2, O3+NO2)and multi-pollutant model(O3+PM2.5+SO2+NO2). A further analysis was conducted based on gender and age group stratification. Results The daily average concentration of O3 was 102 μg/m3, and 8 persons died of respiratory diseases daily. Overall, with 10 μg/m3 increase in the concentration of O3, the ERs for mortality of respiratory diseases were 0.95%(95%CI: 0.28%-1.63%)and 1.70%(95%CI: 0.27%-3.16%)in lag3 and lag05, respectively. There was no statistical difference in ER between male and female, but a significantly higher ER was observed in persons aged ≥65 years. Conclusion There is a positive association between daily O3 and mortality of respiratory diseases in Jinan, especially among people who are above 65 years old.

Key words: Ozone, Respiratory City disease, Mortality, Time series analysis

CLC Number: 

  • R574
[1] 邬堂春. 防控空气污染加强空气污染致健康危害研究[J]. 中华预防医学杂志, 2016, 50(8): 665-667. WU Tangchun. Prevention and control of air pollution needs to strengthen further study on health damage caused by air pollution[J]. Chinese Journal of Preventive Medicine, 2016, 50(8): 665-667.
[2] 钱旭君, 李国星, 贺天锋, 等. 宁波市大气污染物一氧化碳及臭氧对人群心肌梗死死亡的急性效应研究[J].中华流行病学杂志, 2017, 38(3): 297-302. QIAN Xujun, LI Guoxing, HE Tianfeng, et al. Acute effect of air pollutants(carbon monoxide and ozone)on myocardialinfarction mortality in Ningbo[J]. Chinese Journal of Epidemiology, 2017, 38(3): 297-302.
[3] Bert Brunekreef, Stephen T Holgate. Air pollution and health[J]. Lancet, 2002, 360(9341): 1233-1242.
[4] 杨敏娟, 潘小川. 北京市大气污染与居民心脑血管疾病死亡的时间序列分析[J]. 环境与健康杂志, 2008, 25(4): 294-297. YANG Minjuan, PAN Xiaochuan. Time-series analysis of air pollution and cardiovascular mortality in Beijing, China[J]. Journal of Environment and Health, 2008, 25(4): 294-297.
[5] Chan CK, Yao XH. Air pollution in mega cities in China[J]. Atmos Environ, 2008, 42(1): 1-42.
[6] Brook RD, Rajagopalan S, Pope CA, et al. Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American heart association[J]. Circulation, 2010, 121(21): 2331-2378.
[7] 刘昌景, 黄飞, 杨志洲, 等. 我国空气污染物与人群呼吸系统疾病死亡急性效应的Meta分析[J]. 中华流行病学杂志, 2015, 36(8): 889-895. LIU Changjing, HUANG Fei, YANG Zhizhou, et al. A Meta analysis on the associations between air pollution and respiratory mortality in China[J]. Chinese Journal of Epidemiology, 2015, 36(8): 889-895.
[8] 王文韬, 孙庆华, 覃健, 等. 中国5个城市2013-2015年空气质量健康指数模拟研究[J]. 中华流行病学杂志, 2017, 38(3): 314-319. WANG Wentao, SUN Qinghua, QIN Jian, et al.Simulation study of air quality health index in 5 cities in China: 2013-2015[J]. Chinese Journal of Epidemiology, 2017, 38(3): 314-319.
[9] 殷永泉, 单文坡, 纪霞, 等. 济南大气臭氧浓度变化规律[J]. 环境科学, 2006, 27(11): 2299-2302. YIN Yongquan, SHAN Wenpo, JI Xia, et al. Characteristics of Atmospheric ozone in the Urban Area of Jinan[J]. Environment Science, 2006, 27(11): 2299-2302.
[10] 刘芳, 孙明虎. 济南城区夏季近地面臭氧浓度分析[J]. 中国环境管理干部学院学报, 2016, 26(3): 47-50. LIU Fang, SUN Minghu. Analysis on Surface Ozone Concentration in Urban Area of Jinan in Summertime[J]. Journal of the Environmental Management College of China, 2016, 26(3): 47-50.
[11] World Health Organization(WHO). Ambient air pollution: A global assessment of exposure and burden of disease[R]. Geneva: WHO, 2016.
[12] Yang G, Wang Y, Zeng Y, et al. Rapid health transition in China, 1990-2010: findings from the Global Burden of Disease Study 2010[J]. Lancet, 2013, 381(9882): 1987-2015.
[13] 陈仁杰. 复合型大气污染对我国17城市居民健康效应研究[D]. 上海: 复旦大学, 2013.
[14] Srebot V, Gianicolo EA, Rainaldi G, et al. Ozone and cardiovascular injury[J]. Cardiovascular Ultrasound, 2009, 7: 30. doi: 10.1186/1476-7120-7-30.
[15] Wong TW, Tam WS, Yu TS, et al. Associations between daily mortalities from respiratory and cardiovascular diseases and air pollution in HongKong, China[J]. Occup Environ Med, 2002, 59(1): 30-35.
[16] 廖志恒, 范绍佳. 2006~2012年珠江三角洲地区O3污染对人群健康的影响[J]. 中国环境科学, 2015, 35(3): 897-905. LIAO Zhiheng, FAN Shaojia. Human health impact of exposure to ozone pollutant in Pearl River Delta region during 2006-2012[J]. China Environmental Science, 2015, 35(3): 897-905.
[17] 班婕, 李湉湉. 北京市不同度量方式下臭氧短期暴露人群急性健康效应研究[J]. 环境与健康杂志, 2016, 33(4): 287-291. BAN Jie, LI Tiantian. Short-term effects of different ozone metrics on daily mortality in Beijing[J]. Journal of Environment and Health, 2016, 33(4): 287-291.
[18] 崔亮亮, 周敬文, 张军, 等. 灰霾期间常见一般和危重症状的急性效应分析[J]. 环境与健康杂志, 2014, 31(7): 600-603. CUI Liangliang, ZHOU Jingwen, ZHANG Jun, et al. Analysis of acute symptoms in common and critically ill patients during haze event[J]. Journal of Environment and Health, 2014, 31(7): 600-603.
[19] Cui LL, Zhang J, Zhang J, et al. Acute respiratory and cardiovascular health effects of an air pollution event, January 2013, Jinan, China[J]. Public Health, 2016, 131: 99-102. doi: 10.1016/j.puhe.2015.11.003.
[20] Liu P, Wang X, Fan J, et al. Effects of Air Pollution on Hospital Emergency Room Visits for Respiratory Diseases: Urban-Suburban Differences in Eastern China[J]. Int J Environ Res Public Health, 2016, 13(3): 341-353.
[21] Burnett RT, Stieb D, Brook JR, et al. Associations between short-term changes in Nitrogen Dioxide and Mortality in Canadian cities[J]. Arch Environ Health, 2004,59(5):228-236.
[22] Katsouyanni K, Samet JM, Anderson HR, et al. Air pollution and health: a European and North American approach(APHENA)[J]. Res Rep Health Eff Inst, 2009, 142: 5-90.
[23] Hurvich CM, Simonoff JS, Tsai CL. Smoothing parameter selection in nonparametric regression using an improved Akaike information criterion[J]. J Royal Statistical Society. Series B Statistical Methodol, 1998, 60(2): 271-293.
[24] 闫美霖, 李湉湉, 刘晓途, 等. 我国臭氧短期暴露的人群健康效应研究进展[J]. 环境与健康杂志, 2012, 29(8): 752-761. YAN Meilin, LI Tiantian, LIU Xiaotu, et al. Human health effects of short-term ozone exposure: a review of Chinese epidemiological evidence[J]. Journal of Environment and Health, 2012, 29(8): 752-761.
[25] Tao YB, Huang W, Huang X L, et al. Estimated acute effects of ambient ozone and nitrogen dioxide on mortality in the pearl river delta of southern China[J]. Environmental Health Perspectives, 2012, 120(3): 393-398.
[26] 秦萌, 陈英, 李敬芝, 等. 上海市奉贤区主要大气污染物对人群呼吸系统急性健康效应的影响[J]. 东南大学学报(医学版), 2017, 36(2): 197-202. QIN Meng, CHEN Ying, LI Jingzhi, et al. The acute respiratory effects of main air pollutants in Fengxian District of Shanghai[J]. Journal of Southeast University(Medical Science Edition), 2017, 36(2): 197-202.
[27] Mercedes MR, Joel S. Who is More Vulnerable to Die From Ozone Air Pollution[J]. Epidemiology, 2008, 19(5): 672-679.
[28] 晋乐飞, 冯斐斐, 段丽菊, 等. 臭氧对呼吸系统影响研究进展[J]. 中国公共卫生, 2015, 3l(5): 685-688. JIN Yuefei, FENG Feifei, DUAN Liju, et al. Effects of ambient ozone on human respiratory system[J]. Chinese Journal of Public Health, 2015, 3l(5): 685-688.
[1] LIU Ying, YANG Shuxia, SHE Kaili, CHENG Chuanlong, FANG Qidi, HAN Chuang, CUI Feng, LI Xiujun. Cause of death and disease burden of residents of Zibo City, Shandong Province in 2019 [J]. Journal of Shandong University (Health Sciences), 2022, 60(6): 114-121.
[2] Huaiyue XU,Qing WANG,Runmei MA,Jie BAN,Tiantian LI. Temperature-related burden of disease: a review of recent studies [J]. Journal of Shandong University (Health Sciences), 2021, 59(12): 13-19, 32.
[3] YANG Zhen, ZHANG Yanmin, WANG Qianqian, CHEN Huimin, FENG Qiang, ZHOU Shaoying. Correlations of microRNA-103 and microRNA-107 expressions with the clinical characteristics and prognosis of 120 cases of sepsis [J]. Journal of Shandong University (Health Sciences), 2020, 58(12): 77-85.
[4] LI Jing, WANG Chuangxin, XU Xin, YANG Jun, WANG Chunping, XUE Fuzhong, LIU Qiyong. Impacts of ambient temperature on chronic non-communicable disease mortality in Jinan City, China during 2007-2013: an attributable risk study [J]. Journal of Shandong University (Health Sciences), 2018, 56(8): 76-87.
[5] CUI Liangliang, ZHANG Meng, YU Kunkun, JIANG Chao, RUAN Shiman. Acute effects of major air pollutants on emergency calls in Jinan City [J]. Journal of Shandong University (Health Sciences), 2018, 56(11): 34-41.
[6] WANG Zhiqiang, XU Yanlong, XIAO Changchun, FENG Xiaoliang, ZHENG Li, LI Fei, HUANG Fayuan. Time series analysis in ambient PM2.5 pollution and daily cardiovascular mortality in Hefei city during 2014 to 2016 [J]. Journal of Shandong University (Health Sciences), 2018, 56(11): 48-52.
[7] MAN Jinyu, CUI Liangliang, HAN Lianyu, YU Kunkun, WU Xingbin, YUE Kesan, ZHOU Jingwen. Acute effects of ambient particulate matter on local residents’ hospital visits in a heavy air polluted area of Jinan City during 2014-2016 [J]. Journal of Shandong University (Health Sciences), 2018, 56(11): 61-67.
[8] CHEN Lang, ZHAO Chuan, CHEN Fengge, BAI Ping. Effect of airborne particulates concentration on outpatient visits of respiratory diseases among children in Shijiazhuang City [J]. Journal of Shandong University (Health Sciences), 2018, 56(11): 68-75.
[9] XIAO Changchun, TANG Jing, LI Yurong, ZHAI Jinxia. Relationship between air pollutants and outpatient visits due to pneumonia in a childrens hospital in Hefei City: a time series analysis [J]. Journal of Shandong University (Health Sciences), 2018, 56(11): 76-83.
[10] JIA Xiaoqian, CUI Liangliang, YUE Kesan, LI Xinwei, HAN Lianyu, WU Xingbin, ZHOU Jingwen. Time series analysis on the effects of particulate matter on the hospital visits of childrens respiratory diseases in Jinan City [J]. Journal of Shandong University (Health Sciences), 2018, 56(11): 84-90.
[11] YANG Liu, ZHOU Lin, ZHANG Jun, WAGN Ying, LIU Shouqin. Epidemiological characteristics of death caused by road traffic injury in Jinan City during 2011-2015 [J]. Journal of Shandong University (Health Sciences), 2017, 55(12): 77-81.
[12] LI Runzi, ZHANG Tao, LIANG Yumin , LUO Cheng, JIANG Zheng, XUE Fuzhong, LIU Yanxun, LIU Jing, LI Xiujun. Application of SARIMA model in predicting the incidence of mumps [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(9): 82-86.
[13] WANG Ning, DING Guoyong, GAO Lu, LI Jie, LI Xuewen. Influence of meteorological factors on chronic bronchitis mortality of the susceptible population of chronic bronchitis in Pingjiang County, Hunan Province, China [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2015, 53(7): 92-96.
[14] LI Yin-zhu1, XU Wen-jun2, CUI Jing-ying2, REN Cui-ai2. The retrospective analysis of 53 patients with bisphosphonate-related osteonecrosis of the jaw [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2013, 51(1): 109-112.
[15] TANG Hai-rong, YUAN Bin-bin, HU Da-yi, Buaijiaer·Hasimu. Prediction of ankle-brachial index to all-cause and cardiovascular mortalities in patients with high cardiovascular risk [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2013, 51(1): 53-.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Copyright 2018 © Editorial office of Journal of Shandong University (Health Sciences)
Supported by Beijing Magtech Co.Ltd