山东大学学报 (医学版) ›› 2021, Vol. 59 ›› Issue (9): 15-21.doi: 10.6040/j.issn.1671-7554.0.2021.0874
易凡,李亮
YI Fan, LI Liang
摘要： 组织定居性记忆T细胞(TRM)是新近发现的一类不参与体循环,驻留在器官的T淋巴细胞。TRM具有独特的分化调控机制和免疫调节功能,在多种疾病的发生发展中发挥重要作用,有望成为新的治疗靶点。有研究发现TRM存在于肾脏中,因此本文将围绕TRM在肾脏中的形成、表型、维持和作用等方面,综述TRM在肾脏中的最新研究进展。
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