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山东大学学报(医学版) ›› 2017, Vol. 55 ›› Issue (1): 11-15.doi: 10.6040/j.issn.1671-7554.0.2016.1335

• 高龄生育专题 • 上一篇    下一篇

高龄辅助生育技术子代出生缺陷及认知障碍的风险

朱依敏   

  1. 浙江大学医学院附属妇产科医院 生殖内分泌科, 浙江 杭州 310006
  • 收稿日期:2016-10-18 出版日期:2017-01-10 发布日期:2017-01-10
  • 通讯作者: 朱依敏. E-mail: zhuyim@zju.edu.cn E-mail:zhuyim@zju.edu.cn
  • 基金资助:
    浙江省自然科学基金重点资助项目(LZ15H040);浙江省卫生计生委省部共建项目(WKJ-ZJ-1522)

Risk of birth defects and cognitive disorder of children conceived by assisted reproduction technology in couples with advanced parental age

ZHU Yimin   

  1. Department of Reproductive Endocrinology, Womens Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, Zhejiang, China
  • Received:2016-10-18 Online:2017-01-10 Published:2017-01-10

摘要: 随着我国“二孩”政策的全面开放,高龄不孕夫妇助孕比例呈爆发式增长。然而,高龄夫妇助孕风险较高、成功率低下,出生子代的生理和心理健康等问题尤为突出,且遗传风险对人口素质的影响有待进一步追踪。因此,高龄助孕需慎重选择。

关键词: 辅助生殖技术, 高龄, 子代健康

Abstract: Along with the overall implementation of “two-child policy” in our country, the proportion of elder infertile couples seeking for assisted reproductive technology(ART)is increasing dramatically. However, ART for couples with advanced age is associated with low pregnancy rate and high complication rate, and the offsprings physical and mental health problems are prominent. Besides, The genetic risk on population quality still needs to be investigated. Therefore, elder infertile couples should make the decision cautiously when they seek for ART treatment.

Key words: Advanced parental age, Assisted reproduction technology, Offspring health

中图分类号: 

  • R711.6
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