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山东大学学报(医学版) ›› 2017, Vol. 55 ›› Issue (1): 5-10.doi: 10.6040/j.issn.1671-7554.0.2016.1331

• 高龄生育专题 • 上一篇    下一篇

高龄女性生育力评估及辅助生育

邓晓惠,徐亚瑄   

  1. 山东大学齐鲁医院不孕不育诊疗中心, 山东 济南 250012
  • 收稿日期:2016-10-18 出版日期:2017-01-10 发布日期:2017-01-10
  • 通讯作者: 邓晓惠. E-mail:dxh0122@163.com E-mail:dxh0122@163.com
  • 基金资助:
    国家自然科学基金面上项目(81370711);山东省科技攻关项目(2010GSF10814)

Fertility evaluation and assisted reproduction in elder women

DENG Xiaohui, XU Yaxuan   

  1. Infertility Center, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Received:2016-10-18 Online:2017-01-10 Published:2017-01-10

摘要: 女性生育力随年龄下降主要体现在卵巢功能降低和子宫内膜容受性下降,高龄女性应及时接受生育力评估。目前对高龄助孕年龄的界定尚存争议,多数生殖中心将其定为43~45岁。在高龄女性行辅助生殖技术时,重点是增加获卵数和改善卵子质量,无可用卵子的高龄女性可考虑赠卵,同时不要忽视随年龄增加的母婴风险。

关键词: 妊娠结局, 高龄, 辅助生殖技术, 生育力

Abstract: Female fertility declines with age, characterized by poor ovarian function and endometrial receptivity. Therefore, elder women who expect pregnancy should have their fertility evaluated first. At present, there is controversy as to the upper age limit for assisted reproductive technology, which is defined by most infertility centers as 43-45yrs. The focus of ART is to improve the quantity and quality of retrieved oocytes. For women without available oocytes, donation can be an alternative. In addition, age-related maternal and child risks should be taken into consideration.

Key words: Fertility, Assisted reproductive technology, Advanced parental age, Pregnancy outcome

中图分类号: 

  • R711.6
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