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山东大学学报（医学版） ›› 2017, Vol. 55 ›› Issue (1): 22-25.doi: 10.6040/j.issn.1671-7554.0.2016.1332

• 高龄生育专题 • 上一篇    下一篇

高龄女性助孕措施选择

石玉华,李敬   

  1. 山东大学附属生殖医院 国家辅助生殖与优生工程技术研究中心 生殖内分泌教育部重点实验室(山东大学)山东省生殖医学重点实验室, 山东 济南 250001
  • 收稿日期:2016-10-18 出版日期:2017-01-10 发布日期:2017-01-10
  • 通讯作者: 石玉华. E-mail:shiyuhua2003@126.com E-mail:shiyuhua2003@126.com
  • 基金资助:
    国家科技支撑计划(2012BAI32B04);国家自然科学基金面上项目(81471428);山东省科技发展计划(2014GSF118070);山东省人口和计划生育委员会科技计划(2013-03);山东大学附属生殖医院自主创新项目(20141102)

Strategies for infertility treatment in elderly women

SHI Yuhua, LI Jing   

  1. Center for Reproductive Medicine, Shandong University;
    National Research Center for Assisted Reproductive Technology and Reproductive Genetics;
    Key Laboratory of Reproductive Endocrinology(Shandong University), Ministry of Education;
    Shandong Provincial Key Laboratory of Reproductive Medicine, Jinan 250001, Shandong, China
  • Received:2016-10-18 Online:2017-01-10 Published:2017-01-10

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摘要： 高龄女性生育力下降,活产率降低,有生育要求时应及时去医院做相关检查,正确评估生育能力及妊娠相关风险,通过助孕技术,如促排卵指导同房(或人工授精)、选用辅助生殖技术和辅助药物(重组人促黄体生成素、生长激素、辅酶Q10、脱氢表雄酮、雌激素等)及改变生活方式可提高活产率,赠卵可能是最有效的助孕措施。

关键词: 高龄, 体外受精, 不孕, 助孕

Abstract: Women older than 35 years of age should be counseled about age-related fertility decline and high risk of pregnancy complications if they have the desire of fertility. After failed attempts to conceive, in vitro fertilization(IVF), assisted reproductive techniques and adjunct agents may be adopted, including recombinant luteinizing hormone(r-LH), growth hormone(GH), coenzyme Q10(CoQ10), and dehydroepiandrosterone(DHEA). Change of life style may increase live birth rate. Oocyte donation may be the most effective assisted reproductive strategy.

Key words: Infertility, In vitro fertilization, Assisted reproductive technology, Elderly women

中图分类号: 

  • R711.6
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