高龄女性的卵子和胚胎质量

doi:10.6040/j.issn.1671-7554.0.2016.1333

摘要/Abstract

摘要： 高龄女性卵巢储备不足、生育功能低下一直是生殖医学的难题,卵子和胚胎质量的下降是导致高龄女性妊娠率低、流产率高的主要原因。辅助生殖技术可通过促排卵、改进培养方案、胚胎植入前遗传学筛查等技术,以提高高龄女性每周期获得优质卵子和胚胎的机会,从而提高妊娠率。但高龄女性的卵子和胚胎质量难以逆转,年龄因素导致的卵巢功能低下并非目前的医疗手段能够解决,女性应该避免高龄生育。

关键词: 辅助生殖技术, 卵子, 妊娠, 胚胎, 高龄

Abstract: Poor ovarian reserve and low fertility in elder women have been troubling both the patients and doctors. Low oocyte and embryo quality is the primary cause for low pregnancy rate and high abortion rate. Assisted reproductive technology(ART)can help ovarian stimulation, culture protocol modification and preimplantation genetic screening(PGS), which are conducive to obtaining healthy oocytes and embryos per cycle. However, ART is unable to increase the quality of oocytes and embryos derived from elder women. So far, there is no solution available to improve the low 山东大学学报 (医学版)55卷1期 -李梅.高龄女性的卵子和胚胎质量 \=-ovary function in elder women. Therefore, elder women should take it seriously before they decide to conceive.

Key words: Oocyte, Assisted reproductive technology, Embryo, Advanced parental age, Pregnancy

中图分类号:

R711.6

李梅. 高龄女性的卵子和胚胎质量[J]. 山东大学学报（医学版）, 2017, 55(1): 16-21.

LI Mei. Quality of oocytes and embryos of elder women[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(1): 16-21.

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