高通量基因测序技术在淋巴瘤中的应用进展

doi:10.6040/j.issn.1671-7554.0.2019.428

摘要/Abstract

摘要： 近年来,基于全基因组的高通量测序技术发展迅速,由于其速度快、准确率高、成本低等优点,目前已广泛应用在临床医学的各个领域,为亚型众多、治疗复杂的淋巴瘤研究带来了革命性变化,为筛选淋巴瘤的特异性诊断标志、研究疾病的发病机制、寻找预后指标及促进新药研发起到了极大的推动作用。

关键词: 淋巴瘤, 高通量测序, 基因组测序

Abstract: High-throughput sequencing technology based on whole-genome sequences has developed rapidly in recent years. Thanks to its high speed, high accuracy and low cost, it has been widely used in various fields of clinical medicine. It has also brought revolutionary changes for the diagnosis and treatment of numerous subtypes of lymphomas. The high-throughput sequencing has greatly promoted the development of lymphoma research, including screening specific diagnostic markers, exploring the pathogenesis of the diseases, finding prognostic indicators and promoting new drug development.

Key words: Lymphoma, High-throughput sequencing, Gene sequencing

中图分类号:

R733.4

王欣. 高通量基因测序技术在淋巴瘤中的应用进展[J]. 山东大学学报 (医学版), 2019, 57(7): 50-54.

WANG Xin. Development of gene sequencing in the diagnosis and treatment of lymphoma[J]. Journal of Shandong University (Health Sciences), 2019, 57(7): 50-54.

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