Abstract: Objective To provide valuable references for improving the diagnosis and treatment of novel coronavirus pneumonia in Shandong Province. Methods Clinical data of novel coronavirus pneumonia(NCP)patients in Shandong Province until February 15, 2020 were summarized and analyzed to investigate their epidemiological and clinical features and treatment effect. Furthernore, the clinical data of four typical cases were presented in detail. Results The characteristics of the epidemic, clinical symptoms and treatment were basically consistent with the national data. The vast majority of patients were mild, a few were severe, and very few were critically ill because of severe underlying diseases. Clinical features were mainly fever, dry cough, normal or decreased levels of white blood cells, about 50 percent of cases with reduced lymphocyte count, and ground glass opacity in lung in the early stage. The treatment effect was generally satisfactory. Senility and underlying diseases were important risk factors for severe illness. Closely observing the signs of disease progression and early intervention could reduce mortality. Coclusion The incidence of NCP in Shandong Province is relatively high, but the majority are common type, and the severe type is lower than the national average level outside Hubei Province. The survival rate of severe case is high, and the mortality is lower than the national average level outside Hubei Province. The therapeutic experience of Shandong Province should be promoted and applied in China.

Key words: Shandong Province, Novel coronavirus pneumonia, Clinical characteristics, Treatment effect