Journal of Shandong University (Health Sciences) ›› 2022, Vol. 60 ›› Issue (9): 108-112.doi: 10.6040/j.issn.1671-7554.0.2022.0099

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Angiosarcoma of the uterus: a report of 2 cases and literature review

WANG Lihui, GAO Min, KONG Beihua   

  1. Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Published:2022-09-02

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Abstract: Objective To analyze 2 cases of angiosarcoma of the uterus misdiagnosed as other types of uterine malignancies and to review relevant literature, so as to improve the clinicians awareness of the clinicopathological feature, treatment and prognosis of this disease. Methods The clinical data of 2 cases of uterine angiosarcoma were collected and analyzed, and relevant literature was reviewed. Results Case 1 received radical surgery and 6 cycles of ifosfamide + epirubicin chemotherapy after surgery. The postoperative progression-free survival was 62 months and the overall survival was 66 months. Case 2 received radical surgery and 4 cycles of ifosfamide + epirubicin chemotherapy, with no sign of recurrence. Conclusion Angiosarcoma of the uterus is extremely rare in clinical practice and is easily misdiagnosed. It should be differentiated from other uterine malignancies by pathology and immunohistochemistry. The combination of surgery and adjuvant chemotherapy might be effective.

Key words: Angiosarcoma, Uterine malignancy, Misdiagnosis, Therapy, Prognosis

CLC Number: 

  • R737.33
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