Journal of Shandong University (Health Sciences) ›› 2021, Vol. 59 ›› Issue (7): 38-42.doi: 10.6040/j.issn.1671-7554.0.2021.0482

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Risk factors influencing prognosis of lower extremity deep vein thrombosis in pregnant and parturient women

CHEN Liyu1, XIAO Juan2, LYU Xianzhong1, DUAN Baomin1, HONG Fanzhen1   

  1. 1. Department of Obstetrics;
    2. Center of Evidence-based Medicine, The Second Hospital of Shandong University, Jinan 250033, Shandong, China
  • Published:2021-07-16

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Abstract: Objective To investigate the risk factors affecting the prognosis of deep vein thrombosis(DVT)in pregnant and parturient women. Methods Clinical data of 37 pregnant women with DVT who underwent obstetric examination and delivered in The Second Hospital of Shandong University during Dec. 2015 and Jan. 2020 were retrospectively analyzed. According to thrombus status, the subjects were divided into two groups: thrombus disappearance group(n=13)and thrombus residue group(n=24). Independent sample t test, rank sum test(Mann-Whitney U test)and χ2 test were used for univariate analysis of clinical characteristics, laboratory indicators and VTE risk factors score of the two groups. Results The D-dimer was 1 340.50(659.00, 2 447.75)ng/mL in the thrombus disappearance group, and 3 105.00(1 709.50, 6 146.00)ng/mL in the thrombus reside group(P=0.009). VTE risk factors score was 3.31±1.11 in the thrombus disappearance group and 4.96±1.94 in the thrombus residue group(P=0.002). The number of cases complicated with preeclampsia during pregnancy was 0 case(0%)in the thrombus disappearance group and 6 cases(25%)in the thrombus residue group(P=0.038). Conclusion High score of VTE risk factors, complicated preeclampsia and high concentration of D-dimer are the risk factors for residual thrombus in pregnant and maternal DVT patients.

Key words: Deep vein thrombosis, D-dimer, VTE risk factors score, Prognosis and follow-up, Risk factors

CLC Number: 

  • R714.25
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