Abstract: Objective To investigate the significance of 128-slice 4D CT whole liver perfusion imaging in the diagnosis of hepatic tumor. Methods Data of 45 cases of primary liver carcinoma and 40 cases of liver hemangioma obtained from 128 CT of the whole liver perfusion scan were processed with the perfusion software, automatically generating 4D-CTA images. Blood flow (BF), arterial liver perfusion (ALP), portal venous perfusion (PVP) and hepatic perfusion index (HPI) were analyzed. With reference to the parameters, the blood vessels supply of liver tumor, intrahepatic vessel occlusion, stricture and embolism were evaluated. Results ① The BF, ALP and HPI in primary liver carcinoma were obviously higher than those of surrounding lesions within 1cm in hepatic parenchyma (P<0.01); the PVP of primary liver carcinoma reduced significantly; the BF, ALP and HPI of liver hemangioma were higher than those of peripheral parenchymal (P<0.05); the BF and ALP of liver hemangioma lesions were higher than those of primary liver cell cancer focus (P<0.05) and the HPI was lower than that of primary liver cell cancer focus (P<0.05); the PVP of primary liver cell carcinoma focus was reduced compared with liver hemangioma (P<0.01). ② Of the 45 patients with primary liver carcinoma, 28 had cancer of feeding artery; 20 had thickened, rigid, disorder or distorted feeding artery; 14 had portal venous embolism. Of the 40 cases of liver hemangioma, blood vessels were pulled in 23cases. Conclusion 128-slice 4D CT whole liver perfusion imaging can accurately reflect the hemodynamic characteristics of primary hepatic carcinoma and hepatic hemangioma, showing great clinical significance in the early diagnosis, differential diagnosis, choice of surgical approach and prognosis for hepatic tumor.

Key words: Diagnosis, Tomography, Hepatic tumor, CT perfusion imaging