Journal of Shandong University (Health Sciences) ›› 2021, Vol. 59 ›› Issue (2): 66-70.doi: 10.6040/j.issn.1671-7554.0.2020.1177

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Diagnostic value of dual-energy photons CT in gout

GUAN Shuai1, DUAN Shifei2, XIA Xiaona1, MENG Xiangshui1, MA Xiangxing1   

  1. 1. Department of Radiology, Qilu Hospital(Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao 266035, Shandong, China;
    2. Department of Radiology, Qingdao Central Hospital, Qingdao University, Qingdao 266042, Shandong, China
  • Published:2021-03-05

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Abstract: Objective To explore the diagnostic value of dual-energy photons CT in gout. Methods The clinical data of 111 confirmed gout cases were retrospectively analyzed, including 105 males and 6 females. The original CT and GOUT reconstruction images were acquired from dual-energy photons CT scan. In the two kinds of images, the numbers of urate crystals displayed were analyzed with Wilcoxon Matched-Pairs Signed-Ranks Test. The number of urate crystals displayed in GOUT reconstruction images, course of disease, and serum urate level were analyzed with Spearman rank correlation. Results Gout was detected in the feet in 51 cases(45.95%), in the first metatarsophalangeal joints in 30 cases(27.03%), in the knees in 41 cases(36.94%), in the ankles in 12 cases(10.81%), in the hands in 4 cases(3.60%), in the wrists in 2 cases(1.80%), and in the lumber vertebra in 1 case(0.90%). In the original CT images, no abnormal-density nodules were observed in 39 patients(35.14%); single and multiple high-density nodules were observed in 25(22.52%)and 47(42.34%)cases, respectively. In the reconstruction images, single and multiple urate crystals were observed in 45(40.54%)and 66(59.46%)cases, respectively; 15 cases(13.51%)had the same number of urate crystals as in the original images; 96 cases(86.49%)displayed more urate crystals than in the original images. There was statistically significant difference in the number of urate crystals displayed between original and reconstruction images(Z=-8.522, P<0.001). The course of disease ranged from 3 days to 3 years and level of serum urate ranged from 319 to 800 μmol/L. The number of urate crystals displayed in GOUT reconstruction images was significantly correlated with the course of disease and level of serum urate(rs=0.465, 0.433, P<0.001). Conclusion Dual-energy photons CT has a high detection rate of urate crystals, which is helpful in the diagnosis of suspected gout patients.

Key words: Dual energy, Computed tomography, Gout, Urate crystal

CLC Number: 

  • R589.7
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