Abstract: Objective To explore the clinical and radiology characteristics and laboratory test results of medullary sponge kidney(MSK). Methods A total of 8 MSK patients, in whom 2 were two years old or so, 3 ranged from twenty to forty years old, and 3 ranged from forty to sixty-five years old, hospitalized in Qilu Hospital from Jan. 2012 to Dec. 2016, were enrolled. The clinical manifestations, laboratory test results, and radiology characteristics, including X-ray, intravenous pyelography(IVP)and computed tomograph(CT), were analyzed. Results Multiple cystic dilatation could be seen in collecting duct of children, but the radiology signs of the kidney stone were not as obvious as the adult. The patients ranged from 20 to 40 years old had less complications and thicker cortex renis; their pelvis were lightly dropsical. The patients ranged from 40 to 65 years old had thinner cortex renis and more serious hydronephrosis, companied with the increased creatinine level. The staghorn stone surface was smooth along the mucosa while the opposite side was rough. The gas density shadow could be seen in pelvis when it was infected with bacteria. CT and X-ray images showed high density shadows with circle and oval signs ranged in carunculae papillaris and inter medulla regions. IVP images showed the ecstatic collecting tubes and papillary ducts with the line and brush shadow. Conclusion MSK 山 东 大 学 学 报 (医 学 版)56卷3期 -狄钰,等. 髓质海绵肾结石的计算机断层扫描、静脉肾盂造影表现 \=-can be combined with renal tubular acidosis, drying syndrome. Stone grows along the mucosal surface with the parallel, sand-like, and eggshell calcification signs. Stone can overgrow into the pelvis and calyx, and integrate into clusters, which leads to the local hydrops. Laser lithotripsy is needed to improve the kidney function when the hydrops situation is serious, but the stone in papillary ducts is difficult to remove and easily recurrent after the surgery.

Key words: Medulla sponge kidney, Kidney stone, Intravenous pyelography, Computed tomography, Radiology signs