低分子肝素在生殖领域的应用

doi:10.6040/j.issn.1671-7554.0.2024.0727

Abstract

Abstract: Low molecular weight heparin(LMWH)is the most commonly used heparin anticoagulant, which is relatively safe for mother and fetus. At present, LMWH has been widely used in assisted reproduction, and clinical studies have reported its efficacy in preventing thrombosis, increasing embryo implantation rates, reducing the risk of spontaneous abortion, etc. However, the dosage and level of evidence are not clear. This review summarized the relevant studies on the clinical application of LMWH in assisted reproduction, in order to provide relevant reference information for the reasonable application of LMWH in clinic, and to provide ideas for the clinical and basic research of LMWH in the field of assisted reproduction.

Key words: Low molecular weight heparin, Assisted reproductive technology, In vitro fertilization, Recurrent implantation failure, Recurrent spontaneous abortion, Ovarian hyperstimulation syndrome, Polycystic ovary syndrome

CLC Number:

R339.2

WAN Wenjing, GAO Shanshan. Application of low molecular weight heparin in reproductive field[J].Journal of Shandong University (Health Sciences), 2025, 63(6): 117-124.

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