Journal of Shandong University (Health Sciences) ›› 2021, Vol. 59 ›› Issue (8): 38-43.doi: 10.6040/j.issn.1671-7554.0.2021.0935

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Role of immunosuppressants in rheumatic disease-associated recurrent spontaneous abortion

GUO Yunfei, SHU Qiang   

  1. Department of Rheumatology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250012, Shandong, China
  • Published:2021-09-16

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Abstract: One of the main causes of recurrent spontaneous abortion(RSA)is the combination of rheumatologic diseases. In recent years, immunosuppressive agents have gradually taken the main role in the treatment of patients with RSA combined with rheumatologic diseases, and their therapeutic effects are generally recognized. Since RSA combined with rheumatic immune disease involves several disciplines, the indications and dosage of immunosuppressants need to be further standardized. In this paper, we review the existing domestic and international literature in terms of the definition of RSA, the correlation between rheumatic diseases and RSA, and the use of immunosuppressive drugs, in order to improve the readers understanding of related diseases and drugs, and to provide reference for clinicians to make rational decisions in practice.

Key words: Immunosuppressants, Recurrent spontaneous abortion, Rheumatic diseases, Rheumatoid arthritis, Systemic lupus erythematosus, Connective tissue disease

CLC Number: 

  • R593.2
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