Journal of Shandong University (Health Sciences) ›› 2025, Vol. 63 ›› Issue (2): 84-94.doi: 10.6040/j.issn.1671-7554.0.2024.0579

• Public Health & Preventive Medicine • Previous Articles     Next Articles

Short-term effects of air pollution on the year of life lost due to ischemic stroke and the modifying effects of extreme temperature events in Zibo City

SONG Sihao1, CHENG Chuanlong1, LI Shufen1, XI Rui1, LIANG Kemeng1, NI Zhisong1, CUI Feng2, LI Xiujun1   

  1. 1. Department of Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, Shandong, China;
    2. Zibo Center for Disease Control and Prevention, Zibo 255026, Shandong, China
  • Online:2025-03-10 Published:2025-03-07

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Abstract: Objective To investigate the relationships between short-term exposure to air pollutants and the year of life lost(YLL)due to ischemic stroke, and test the modifying effects of extreme temperature events. Methods Daily ischemic stroke mortality data, meteorological data, and air pollution data were collected from January 1, 2015, to December 31, 2019, in Zibo City. The YLL was calculated using standard life tables. Generalized additive models were adopted to test the effects of air pollutants on YLL. Subgroup analyses were conducted to identify vulnerable population. Stratified analyses were conducted to identify the modifying effects of extreme temperature events. Results PM2.5 at lag0 and lag01 were significantly associated with an increase of YLL due to ischemic stroke, and for every 10 μg/m3 increase in PM2.5 concentration, the increases in YLL due to ischemic stroke were 0.56(95%CI: 0.05-1.07)and 0.66(95%CI: 0.06-1.25), respectively. PM10 at lag4, lag01, lag04, and lag05 also showed significant positive associations with YLL due to ischemic stroke, and for every 10 μg/m3 increase in PM10 concentration, increases in YLL due to ischemic stroke were 0.40(95%CI: 0.05-0.75), 0.40(95%CI: 0.01-0.79), 0.67(95%CI: 0.12-1.23)and 0.74(95%CI: 0.13-1.35), respectively. No significant association was observed between O3, and YLL in the overall population(P>0.05), however, females and those aged ≥ 65 years were more susceptible to O3, leading to increased YLL in ischemic stroke patients. The associations of SO2, NO2, and CO with YLL due to ischemic stroke were not statistically significant(P>0.05). Furthermore, during cold seasons(from October to March each year), cold spells may mask the adverse health effects of PM2.5. Under a specific cold wave definition, the adverse health effects of PM2.5 on non-cold spell days were greater than on cold spell days, and this difference was statistically significant(P<0.05). Conclusion Short-term exposure to PM10 and PM2.5 increases the YLL due to ischemic stroke, and the harmful health effects of PM2.5 are higher on non-cold spell days. Women and individuals aged ≥ 65 are more susceptible to O3 exposure. Improving air quality helps prevent premature death due to ischemic stroke, particularly by strengthening protection on non-cold spell days and safeguarding vulnerable populations.

Key words: Ischemic stroke, Year of life lost, Air pollution, Extreme temperature event, Lag effects

CLC Number: 

  • R12
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