Journal of Shandong University (Health Sciences) ›› 2020, Vol. 58 ›› Issue (10): 60-65.doi: 10.6040/j.issn.1671-7554.0.2020.0690

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Risk factors of severe and critical patients with COVID-19 in Hubei, China

LIU Jun1*, LI Huan2*, ZHANG Shiyu2, ZHANG Peng3, AI Siqi2, TIAN Fei2, LIN Hualiang2   

  1. 1. Central Office, Qianjiang Center for Disease Control and Prevention, Qianjiang 433100, Hubei, China;
    2. Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, Guangdong, China;
    3. Institute of Preventive Medicine Information, Hubei Provincial Center for Disease Control and Prevention, Wuhan 430000, Hubei, China
  • Published:2020-10-08

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Abstract: Objective To investigate the risk factors of severe and critical patients with coronavirus disease 2019(COVID-19)in Hubei, China. Methods All patients with COVID-19 registered in the National Legal Infectious Disease Reporting System of Hubei Provincial Center for Disease Control and Prevention, as of March 18, 2020, were recruited. According to the symptoms, the patients were divided into two groups: mild/moderate patients and severe/critical patients. Their general characteristics were described, and the risk factors of severe and critical patients with COVID-19 were explored by using a Logistic regression model. Results A total of 48 814 cases were included, of which 38 730 were mild/moderate patients and 10 084 were severe/critical patients. The median age was 54(41, 65)years. Multivariate analysis showed that the elderly, male, home workers, people in Wuhan City, migrants, longer interval between onset and diagnosis, low temperature, higher concentrations of PM2.5/PM10/SO2/O3 increased the risk of severe/critical diagnosis in patients with COVID-19. Conclusion The elderly, male, home workers, people in Wuhan City, migrants, longer interval between onset and diagnosis, low temperature, and air pollution exposure are risk factors for severe/critical COVID-19 patients. More attention should be paid to people with these characteristics.

Key words: Coronavirus disease 2019, Severe patients, Critical patients, Low temperature, Air pollution

CLC Number: 

  • R184
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