Journal of Shandong University (Health Sciences) ›› 2022, Vol. 60 ›› Issue (9): 35-41.doi: 10.6040/j.issn.1671-7554.0.2022.0973

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Progress on assisted reproductive technology for women with atypical endometrial hyperplasia and endometrial carcinoma receiving fertilitysparing treatment

LU Qun1, ZHAO Lulu2   

  1. 1. Medical Center for Human Reproduction, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China;
    2. Department of Obstetrics and Gynecology, Beijing Jishuitan Hospital, Beijing 100035, China
  • Published:2022-09-02

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Abstract: As the incidences of endometrial carcinoma(EC)and atypical endometrial hyperplasia(AEH)are rising and patients tend to be younger, the demand for fertility preservation is also increasing. Although fertility-preserving therapy based on high-dose progesterone has achieved high rate of complete response(CR), fertility remains low. Pregnancy for women with EC/AEH has attracted attention, but there is a lack of systematic research for increasing pregnancy after fertility-sparing treatment for women with EC and AEH. The paper focuses on the optimal time of initiating in vitro fertilization and embryo transfer(IVF-ET), appropriate ovarian stimulation protocol in women after fertility-sparing treatment for EC and AEH and the difficulties during IVF-ET.

Key words: Endometrial cancer, Fertility preservation, Pregnancy assistance strategies, Letrozole, Levonorgestrel-releasing intrauterine devices

CLC Number: 

  • R711.6
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