Journal of Shandong University (Health Sciences) ›› 2020, Vol. 58 ›› Issue (4): 54-57.doi: 10.6040/j.issn.1671-7554.0.2020.260

Previous Articles    

Analysis of a family cluster outbreak of coronavirus disease 2019 in Jinan City

WANG Weiru1, LI Xinrui1, WANG Fang2, ZHAO Xiaodong1, YU Qiuyan1, YANG Guoliang1, LI Zhan1, CHANG Caiyun1, ZHAO Mengjiao1, LIU Xiaoxue1, LI Chuanbin1, SUN Zhan1, GENG Xingyi1   

  1. 1. Jinan Center for Disease Control and Prevention, Jinan 250021, Shandong, China;
    2. Prevention and Control Center of Jinan City Tianqiao Distnct, Jinan 250031, Shandong, China
  • Published:2022-09-27

PDF (PC)

18

Abstract: Objective To analyze the transmission chain of a family cluster outbreak of coronavirus disease 2019(COVID-19)in Jinan City in order to provide scientific basis for the prevention and control strategies. Methods According to the “COVID-19 Diagnosis and Treatment Plan”, the first case was investigated to track the close contacts and analyze the transmission chain. Close contacts received 2019-nCoV nucleic acid test. Results A total of 5 cases were tracked, including 3 common cases, 1 mild case and 1 asymptomatic case. The first case had onset on Jan. 25, 2020, and the other cases had onset 4 to 7 days later. All family members lived and dined together, which imposed high risk of transmission. Cases B, C, D and E were second generation cases, and the transmission chain was clear. It was obviously a family cluster. Conclusion Early detection of the infection source and screening of close contact are significant for the prevention and control of COVID-19. Strategies of early detection, early report, early quarantine and early diagnosis should be strictly implemented.

Key words: Novel coronavirus pneumonia, Clustering, Transmission chain, Prevention and control

CLC Number: 

  • R511
[1] 中国疾病预防控制中心. 2019新型冠状病毒疫情进展和风险评估[EB/OL]. [2020-02-10]. http://www.chinacdc.cn/yyrdgz/ 202001/P020200128523354919292.pdf.
[2] 中华预防医学会新型冠状病毒肺炎防控专家组. 新型冠状病毒肺炎流行病学特征的最新认识[J]. 中华流行病学杂志, 2020, 41(2): 139-144. Special Expert Group for Control of the Epidemic of Novel Coronavirus Pneumonia of the Chinese Preventive Medicine Association. An update on the epidemiological characteristics of novel coronavirus pneumonia(COVID-19)[J]. Chinese Journal of Epidemiology, 2020, 41(2): 139-144.
[3] 中华人民共和国国家卫生健康委员会.《中华人民共和国国家健康委2020年第1号公告》[EB/OL]. [2020-01-20]. http://www.nhc.gov.cn/jkj/s7916/202001/44a3b8245e-8049d2837a4f27529cd386.shtml.
[4] 中华人民共和国国家卫生健康委员会.《新型冠状病毒肺炎防控方案(第五版)》[EB/OL]. [2020-02-21]. http://www.nhc.gov.cn/jkj/s3577/202002/a5d6f7b8c48c-451c87dba14889b30147.shtml.
[5] 陈伟, 王晴, 李媛秋, 等. 我国新型冠状病毒肺炎疫情早期围堵策略概述[J]. 中华预防医学杂志, 2020, 54(3): 239-244. CHEN Wei, WANG Qing, LI Yuanqiu, et al. Early containment strategies and core measures for prevention and control of novel coronavirus pneumonia in China[J]. Chinese Journal of Preventive Medicine, 2020, 54(3): 239-244.
[6] Phan LT, Nguyen TV, Luong QC, et al. Importation and human-to-human transmission of a novel coronavirus in Vietnam [J]. N Engl J Med, 2020. doi:10.1056/nejm C2001272.
[7] Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China [J]. Lancet, 2020. doi:org/10.1038/s4142 1-020-0148-0.
[8] 白少丽, 王建云, 周莹荃, 等. 甘肃省首起新型冠状病毒肺炎家庭聚集性疫情分析[J]. 中华预防医学杂志, 2020, 54(4): 1-3. BAI Shaoli, WANG Jianyun, ZHOU Yingquan, et al. Analysis of the first cluster of cases in a family of novel coronavirus pneumonia in Gansu Province[J].Chinese Journal of Preventive Medicine, 2020, 54(4): 1-3.
[9] 中国疾病预防控制中心新型冠状病毒肺炎应急响应机制流行病学组.新型冠状病毒肺炎流行病学特征分析[J]. 中华流行病学杂志, 2020, 41(2): 145-151. Epidemiology Working Group for NCIP Epidemic Reponse, Chinese Center for Disease Control and Prevention.The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases(COVID-19)in China[J].Chinese Journal of Epidemiology, 2020, 41(2): 145-151.
[10] Ai T, Yang Z, Hou H. Correlation of chest CT and RT-PCR testing in coronavirus disease 2019(COVID-19)in China: a report of 1014 Cases [J]. Radiology, 2020. doi: 10.1148/radiol.2020200642.
[11] Liu K, Fang YY, Deng Y, et al. Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province [J]. Chin Med J, 2020. doi:10.1097/cm9.00000000000744.
[12] Chan JF, Yuan S, Kok KH, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster [J]. Lancet, 2020. doi: 10.1016/S0140-6736(20)30154-30159.
[13] 崔亮亮, 耿兴义, 赵小冬, 等. 济南市现阶段新型冠状病毒肺炎的流行特征与思考[J]. 山东大学学报(医学版),2020, 58(3):52-57. CUI Liangliang, GENG Xingyi, ZHAO Xiaodong, et al. Reflection and epidemiological characteristics of coronavirus disease 2019 in Jinan City[J]. Journal of Shandong University(Health Sciences), 2020, 58(3): 52-57.
[14] Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China [J]. Lancet, 2020, 395(10223): 497-506.
[15] Kang M, Wu J, Ma W, et al. Evidence and characteristics of human to human transmission of SARS-CoV-2 [J]. medRxiv, 2020. https://doi. org/10.1101/ 2020.02.03.20019141.
[16] Riou J, Althaus CL. Pattern of early human to human transmission of Wuhan 2019 novel coronavirus(2019-nCoV), December 2019 to January 2020 [J]. Euro Surveill, 2020, 25(4): 2000058. doi: 10.2807/1560-7917.ES.2020.25.4.2000058.
[17] 欧剑鸣, 叶雯婧, 郑奎城, 等. 福建省新型冠状病毒肺炎流行病学特征分析[J]. 中国人兽共患病学报, 2020. doi:10.3969/j.issn.1002-2694.2020.00.029. OU Jianming,YE Wenjing, ZHENG Kuicheng,et al. Epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases(COVID-19)in FuJian,China[J]. Chinese Journal of Zoonoses, 2020. doi:10.3969/j.issn.1002-2694.2020.00.029.
[18] 李士雪,单莹. 新型冠状病毒肺炎研究进展述评[J]. 山东大学学报(医学版),2020,58(3):19-25. LI Shixue, SHAN Ying. Latest research advances on novel coronavirus pneumonia[J]. Journal of Shandong University(Health Sciences), 2020, 58(3): 19-25.
[1] JING Rui, LIU Tiecheng, WANG Chunrong, HU Yanxia, WU Jingjing, ZHANG Wenqian, GENG Xingyi, RUAN Shiman. Investigation and analysis of a cluster of COVID-19 associated with exposure to a shopping mall in Jinan City [J]. Journal of Shandong University (Health Sciences), 2020, 58(4): 40-43.
[2] YANG Liu, LI Zhan, XU Huaru, CHANG Caiyun, LIU Zhong, LI Chuanbin, SUN Zhan, JING Rui, LIU Tiecheng, GENG Xingyi, ZHOU Jingwen. Epidemiological and clinical characteristics of 10 children with coronavirus disease(COVID-19)in Jinan City [J]. Journal of Shandong University (Health Sciences), 2020, 58(4): 36-39.
[3] LI Xinrui, GENG Xingyi, WANG Weiru, ZHAO Xiaodong, LIU Lanzheng, ZHANG Xiaofei, LÜ Cuixia, CHANG Caiyun, LI Zhan, CUI Liangliang, RUAN Shiman. Consideration about cluster epidemic of 37 COVID-19 cases [J]. Journal of Shandong University (Health Sciences), 2020, 58(4): 32-40.
[4] ZHANG Xiaoguo, MA Yan, XIAO Jiaan, ZHANG Zhongfa. Clinical characteristics of novel coronavirus pneumonia in children in Jinan [J]. Journal of Shandong University (Health Sciences), 2020, 58(3): 62-64.
[5] ZHOU Shengyu, WANG Chunting, ZHANG Wei, WANG Ximing, DONG Liang. Clinical characteristics and treatment effect of 537 cases of novel coronavirus pneumonia in Shandong Province [J]. Journal of Shandong University (Health Sciences), 2020, 58(3): 44-51.
[6] JU Xiuli. Potential mechanism and research progress of mesenchymal stem cells in the treatment of 2019 novel coronavirus pneumonia [J]. Journal of Shandong University (Health Sciences), 2020, 58(3): 32-37.
[7] LI Shixue, SHAN Ying. Latest research advances on novel coronavirus pneumonia [J]. Journal of Shandong University (Health Sciences), 2020, 58(3): 19-25.
[8] Working Team of Prevention and Control for Coronavirus Disease 2019, Qilu Hospital of Shandong University. Strategy and practice of coronavirus disease 2019 prevention and control system in Qilu Hospital of Shandong University [J]. Journal of Shandong University (Health Sciences), 2020, 58(3): 8-18.
[9] Consensus Group of Diagnosis and Treatment for Coronavirus Disease 2019, Qilu Hospital of Shandong University. Diagnosis, management, prevention and control for suspected cases of coronavirus disease 2019, Qilu Hospital criteria [J]. Journal of Shandong University (Health Sciences), 2020, 58(3): 1-7.
[10] LIU Lili, JIA Yan, QI Chang, ZHU Yuchen, LI Chunyu, SHE Kaili, LIU Tingxuan, LI Xiujun. Clustering distribution of COVID-19 in Wenzhou from January to March 2020 based on spatiotemporal analysis [J]. Journal of Shandong University (Health Sciences), 2020, 58(10): 82-88.
[11] LIU Tingxuan, QI Chang, SHE Kaili, JIA Yan, ZHU Yuchen, LI Chunyu, LIU Lili, WANG Xu, ZHANG Zhihua, LI Xiujun. Epidemiological characteristics and spatial-temporal clustering of COVID-19 in Hebei Province [J]. Journal of Shandong University (Health Sciences), 2020, 58(10): 74-81.
[12] LI Chunyu, ZHU Yuchen, QI Chang, LIU Lili, ZHANG Dandan, WANG Xu, XU Xueli, LI Xiujun. Epidemic dynamics of COVID-19 in Xinyang City, Henan Province [J]. Journal of Shandong University (Health Sciences), 2020, 58(10): 38-43.
[13] WANG Runmei, YANG Qiuhong, ZHANG Fang, MA Yuyan. Long-term prognosis of women preeclampsia and risks of incidence in their female offspring [J]. Journal of Shandong University (Health Sciences), 2017, 55(12): 31-35.
[14] LIU Yun-Xia, Li-Shi-Xue, Wang-Zhong-Dong, Xue-Fu-Zhong. A clustering study on tuberculosis based on spacetime permutation scanning statistics [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2009, 47(12): 122-125.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Copyright 2018 © Editorial office of Journal of Shandong University (Health Sciences)
Supported by Beijing Magtech Co.Ltd