Journal of Shandong University (Health Sciences) ›› 2019, Vol. 57 ›› Issue (6): 27-32.doi: 10.6040/j.issn.1671-7554.0.2019.494

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Malignant transformation of endometriosis

LIU Chongdong, LOU Tong, DONG Jing   

  1. Department of Gynaecology and Obstetrics, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China
  • Published:2022-09-27

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Abstract: Endometriosis, characterized by the presence of extra-uterine endometrium, is a common gynecologic disorder in reproductive-age women. In clinical practice, although endometriosis is recognized as a benign disease, it still has the risk of malignant change. This review mainly presents the relationship between endometriosis and ovarian tumors, and probes into the risk factors, molecular mechanism and prevention of malignant transformation.

Key words: Malignant transformation, Endometriosis, Ovarian tumor, Tumor suppressor genes, Oxidative stress

CLC Number: 

  • R737.3
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