JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2016, Vol. 54 ›› Issue (6): 69-72.doi: 10.6040/j.issn.1671-7554.0.2015.1099

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Influencing factors on the curative effect of microvascular decompression in the treatment of primary trigeminal neuralgia

ZHANG Bin, ZHANG Liangwen, CHI Lingyi, WANG Chuanwei, ZHU Shugan   

  1. Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Received:2015-11-11 Online:2016-06-20 Published:2016-06-20

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Abstract: Objective To explore the influencing factors on the curative effect of microvascular decompression(MVD)in the treatment of primary trigeminal neuralgia(TN). Methods MVD was performed in 153 primary TN patients. The independent risk factors on the curative effect were evaluated by single factor analysis of chi-square test and Logistic regression analysis. Results (1) Pain vanished in 125 cases, obviously relieved in 26 cases, and remained unchanged in 2 cases. (2) The artery was compressed in 103 cases, complicated with venous conflict in 49 cases, and 1 case had no obvious conflict. The pain-free rate of venous conflict(71%)was significantly lower than that of artery compression alone(81%, P<0.05). (3) The pain-free rate of V2 was significantly lower than others(P<0.05). Half of the patients with V2 had their NVC at the ventral site of the nerve(P<0.05). (4) Logistic regression analysis showed the vein and V2 were independent risk factors on the curative effect. Conclusion Patients with venous compression or V2 pain have poor curative effect. Venous compression and V2 pain are the independent risk factors. The ventral site is the crucial conflict site of V2, which can serve as a new target for the study of refractory trigeminal neuralgia.

Key words: Primary trigeminal neuralgia, Maxillary branch, Vein, Microvascular decompression, Analysis of curative effect

CLC Number: 

  • R651.1
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