JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2015, Vol. 53 ›› Issue (5): 71-74.doi: 10.6040/j.issn.1671-7554.0.2014.787

Previous Articles     Next Articles

Treatment of coronary heart diseases complicated with carotid arteriostenosis with coronary artery bypass grafting plus carotid endarterectomy

QU Qingxi, ZHAO Xin, SUN Wenyu, SONG Guangmin, MENG Xiangbin, BI Yanwen   

  1. Department of Cardiac Surgery, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Received:2014-11-04 Revised:2015-02-28 Online:2015-05-10 Published:2015-05-10

Abstract: Objective To summarize the clinic experiences of coronary artery bypass grafting (CABG) and carotid endarterectomy (CEA) in the treatment of carotid arteriostenosis and coronary heart diseases, and investigate the operation approaches and curative effects. Methods Clinical data of 22 patients with carotid arteriostenosis complicated with coronary artery diseases who underwent CEA and CABG during July 2008 and Nov 2013 in Qilu Hospital of Shandong University were retrospectively reviewed. Results One patient who underwent double valve replacement due to renal failure died. No cerebral complications were found during the perioperative period. A total of 20 patients (95.2%, 20/21) were followed up for 12-76 months (mean 44.3±20.2 months). Angina occurred in 1 patient three years after operation, while other patients had no symptoms of angina, and their cardiac function were improved significantly. No stroke was found. Of the 16 patients who had severe brain ischemia, the symptoms were remarkably improved after the surgery. Carotid duplex ultrasound or carotid CTA results showed that carotid arteries were widened, and blood flow was smooth. There were statistical differences in blood flow velocity, diameter of vessels and left ventricular ejection fraction (LVEF) before and after operation (P<0.05). Conclusion Concomitant CABG and CEA is safe and effective for patients with carotid arteriostenosis and coronary artery diseases.

Key words: Coronary artery bypass grafting, Carotid endarterectomy, Carotid arteriostenosis, Coronary heart disease

CLC Number: 

  • R654.2
[1] Venkatachalam S, Gray BH, Mukherjee D, et al. Contemporary management of concomitant carotid and coronary artery disease[J]. Heart, 2011, 97(3): 175-180.
[2] Brown KR. Treatment of concomitant carotid and coronary artery disease. Decision-making regarding surgical options[J]. J Cardiovasc Surg, 2003, 44(3): 395-399.
[3] Kihara S, Shimakura T, Tanaka SA, et al. Staged coronary artery bypass grafting after percutaneous angioplasty for intracranial vascular stenosis[J]. J Thorac Cardiovasc Surg, 2001, 122(3): 608-610.
[4] Naylor AR, Bown MJ. Stroke after cardiac surgery and its association with asymptomatic carotid disease: an updated systematic review and meta-analysis[J]. Eur J Vasc Endovasc Surg, 2011, 41(5): 607-624.
[5] Peter Ogutu, Raphael Werner, Frank Oertel, et al. Should patients with asymptomatic significant carotid stenosis undergo simultaneous carotid and cardiac surgery?[J]. Interact Cardiovasc Thorac Surg, 2014, 18 (4): 511-518.
[6] Mićović S, Boković S, Sagić D, et al. Simultaneous hybrid carotid stenting and coronary bypass surgery versus concomitant open carotid and coronary bypass surgery: a pilot, feasibility study[J]. Eur J Cardiothorac Surg, 2014, 46(5): 857-862.
[7] Fareed KR, Rothwell PM, Mehta Z, et al. Synchronous carotid endarterectomy and off-pump coronary bypass: an updated, systematic review of early outcomes[J]. Eur J Vasc Endovasc Surg, 2009, 37(4): 375-378.
[8] Kernan WN, Ovbiagele B, Black HR, et al. Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association[J]. Stroke, 2014, 45(7): 2160-2236.
[9] Eagle KA, Guyton PA, Davidoff R. 2004 guideline update for coronary artery bypass graft surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery)[J]. Circulation, 2004, 110(14): 340-437.
[10] Norkiene I, Samalavicius R, Misiüriene I. Incidence and risk factors for early postoperative cognitive decline after coronary artery bypass grafting[J]. Medicina, 2010, 46(7): 460-464.
[11] Brott TG, Halperin JL, Abbara S, et al. 2011ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: executive summary[J]. Stroke, 2011, 42(8): 420-463.
[12] Hillis LD, Smith PK, Anderson JL, et al. 2011 ACCF/AHA guideline for coronary artery bypass graft surgery: a report of the American college of cardiology foundation/American heart association task force on practice guidelines developed in collaboration with the American association for thoracic surgery, society of cardiovascular anesthesiologists, and society of thoracic surgeons[J]. J Am Coll Cardiol, 2011, 58(24): 123-210.
[13] 李明, 孙立忠, 常谦, 等. 冠状动脉旁路移植同期颈动脉内膜剥脱术[J]. 中国心血管病研究杂志, 2004, 2(1): 14-16. LI Ming, SUN Lizhong, CHANG Qian, et al. Simultaneous carotid endarterectomy and coronary artery bypass grafting[J]. Chinese Journal of Cardiovascular Review, 2004, 2(1): 14-16.
[14] 孟祥斌, 毕研文, 冯进波, 等. 核因子κB的小干扰RNA防治自体移植静脉再狭窄的实验研究[J].山东大学学报: 医学版, 2010, 48(11): 74-80. MENG Xiangbin, BI Yanwen, FENG Jinbo, et al. Research of nuclear factor-κB siRNA to prevent proliferation and restenosis of vein grafts[J]. Journal of Shangdong University: Health Sciences, 2010, 48(11): 74-80.
[15] 赵宏磊. 冠状动脉旁路移植术后早期应用低分子肝素的临床意义[D]. 山东大学, 2012. DOI:10.7666/d.y2182866.
[1] WANG Chunxia, XU Yibo, YANG Ning, XIA Bing, WANG Ping, XUE Fuzhong. A prediction model for coronary heart disease risks based on health management cohort [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(6): 66-71.
[2] LIANG Fei, ZHANG Wenlong, ZHANG Jun, XU Chongen, ZOU Chengwei. Relevant factors and early complications of significantly elevated enzymes after off-pump coronary artery bypass grafting [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(10): 71-75.
[3] YE Cong. Influencing factors for the graft patency of radial artery after coronary artery bypass grafting surgery [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(8): 34-38.
[4] LIU Tianjiao, GUO Yuan, LI Tingting, ZHANG Jianning, LI Jun, ZHANG Peng. Association of serum CTRP9 and APN levels with acute coronary syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2014, 52(9): 58-62.
[5] JIANG Hongmei1,2, CHEN Wenqiang1. Clinical implication of psychotherapy on elderly patients with coronary heart failure undergoing rehabilitation [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2014, 52(4): 85-88.
[6] ZHOU Lu, ZHAO Xin, SUN Wen-yu, BI Yan-wen, BING Wei-dong, BAI Xiao. Open minimally invasive surgery to achieve grafts for coronary artery bypass surgery [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2013, 51(4): 34-36.
[7] ZHANG Xu-ping, ZHANG Dong, LI Zi, LIU Lu-qi. Research on the relationship between diabetes mellitus and in-situ saphenous vein disease [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2013, 51(11): 66-70.
[8] CHEN Wei, TAN Hong, LI Xiao-yan, YANG Yan, WEI Xiu-ying, CHEN Ying-jian, ZHANG Hong-ming. Quantity variance of endothelial progenitor cells in peripheral blood of patients
with coronary heart disease and its influence on endothelial function
[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2012, 50(8): 73-76.
[9] YUAN Xin, ZHENG Zhe, HU Sheng-shou. Application value of EuroSCORE in predicting readmission
after coronary artery bypass graft
[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2012, 50(8): 77-80.
[10] CHEN Jing1, GENG Hou-fa2, SUN Lin2. Correlation between FTO rs9939609 polymorphism and type 2 diabetes mellitus patients with coronary heart disease [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2012, 50(7): 10-.
[11] ZHU Qing1,3, KANG Wei-qiang1,2, GE Zhi-ming4, SONG Da-lin2, WANG Hai-bin2, REN Guo-rui2. Relation of glycated serum album and vulnerable plaque  characteristics in patients with CHD [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2011, 49(7): 100-104.
[12] WANG Chun, GU Tianxiang, YU Yang, SONG Lai-chun, ZHANG Yu-hai, FANG Qin. Retrospective analysis of the relationship between high risk predicted by  EuroSCORE and low operative mortality in 1290 cases of OPCAB surgery [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2011, 49(7): 109-.
[13] SUN Jie, REN Jian-Min, CHEN Chao, LIU Chang-Sheng, SI Qing-Ying. [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2009, 47(5): 102-105.
[14] CHANG Li-Rong, ZHOU Gui-Xia, BI Ti-Juan. Determination of serum visfatin level in type 2 diabetes mellitus complicated with coronary heart disease and its influencing factors [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2009, 47(12): 6-8.
[15] ZHANG Yu-Gong, LI Gui-Shuang, LI Hai-De. Abnormal heart rate recovery in patients with diabetes mellitus or coronary heart disease and its diagnostic value for coronary heart disease [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2009, 47(12): 9-12.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!