JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2014, Vol. 52 ›› Issue (11): 38-40.doi: 10.6040/j.issn.1671-7554.0.2014.372

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Predictive value of umbilical cord blood in combination with peripheral artery blood pH for neonatal hypoxic ischemia encephalopathy

SHAO Qin1, DIAO Yuqiao2   

  1. 1. Department of Pediatrics, Xingtai People's Hospital Affiliated to Hebei Medical University, Xingtai 054000, Hebei, China;
    2. Department of Pediatrics, the Forth Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei, China
  • Received:2014-06-05 Published:2014-11-10

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Abstract: Objective To explore the predictive value of pH in umbilical blood and peripheral arterial blood for the occurring of neonatal hypoxic-ischemic encephalopathy(HIE). Methods pH value of umbilical arterial blood was measured in 917 cases of full-term neonates, sampled during June 2011 to June 2013, before the first cry. Blood gas was analyzed with peripheral arterial blood, sampled at 1 hour after born, from 138 cases whose Apgar scores were less or equal to 7. The effectiveness of HIE detection was compared among umbilical blood, peripheral arterial blood and their combination. Results When umbilical arterial blood pH<7.10 was used as an indicator for HIE diagnosis, the positive prediction value was 55.38%, sensitivity was 60.00% and specificity was 96.61%. When pH value of umbilical arterial blood and arterial blood was used together as the indicator for HIE, the positive prediction value was 95.74%, sensitivity was 88.26% and specificity was 97.10%. Conclusion pH value of peripheral arterial blood is suggested to be determined for new borns whose umbilical arterial blood pH was less than 7.10. The combination of the two indexes can be used to objectively evaluate HIE.

Key words: Cord blood, Blood gas analysis, Hypoxic ischemia encephalopathy, Artery blood, Neonatal

CLC Number: 

  • R722
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