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山东大学学报 (医学版) ›› 2023, Vol. 61 ›› Issue (7): 83-89.doi: 10.6040/j.issn.1671-7554.0.2022.1317

• 临床医学 • 上一篇    

不同频率重复经颅磁刺激治疗脑梗死后失语症的疗效

李国华1,陆艺2,王胜秋1   

  1. 1.济南市第三人民医院康复医学科, 山东 济南 250132;2.山东省精神卫生中心物理治疗科, 山东 济南 250014
  • 发布日期:2023-07-04
  • 通讯作者: 李国华. E-mail:doctorgogo@163.com
  • 基金资助:
    济南市卫生健康委员会科技计划(2020-4-38)

Effects of different frequencies of repetitive transcranial magnetic stimulation on aphasia in postcerebral infarction patients

LI Guohua1, LU Yi2, WANG Shengqiu1   

  1. 1. Department of Rehabilitation Medicine, The Third Hospital of Jinan, Jinan 250132, Shandong, China;
    2. Department of Physiotherapy, Shandong Mental Health Center, Jinan 250014, Shandong, China
  • Published:2023-07-04

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摘要： 目的 观察不同频率重复经颅磁刺激(rTMS)治疗脑梗死失语症的临床疗效。 方法 将脑梗死后失语症患者随机分为3组,给予低频rTMS治疗(1Hz)、高频rTMS(10Hz)及单纯语言康复,分别对3组患者治疗前、治疗2周、4周及12周进行语言功能评估,以观察不同频率rTMS治疗脑梗死后失语的临床疗效。 结果 三组患者各评估指标均随治疗时间呈现好转趋势,听词指图、失语商(AQ)在12周达高峰,余指标在4周达高峰(P<0.05);同一治疗时间组间比较,rTMS两组效果优于单纯治疗组(P<0.05);治疗2周、4周评估时,高频治疗组视图命名时间短于低频治疗组,治疗2周、4周及12周评估时,低频治疗组视图命名成绩高于高频治疗组(P<0.05)。 结论 不论低频刺激还是高频刺激,rTMS在治疗脑梗死后失语症方面起着积极作用,治疗效果略有区别:高频治疗组视图命名时间短于低频治疗组,后者视图命名成绩高于前者。

关键词: 重复经颅磁刺激, 高频, 低频, 脑梗死, 失语

Abstract: Objective To compare the efficacy of different frequencies of repetitive transcranial magnetic stimulation(rTMS)in the treatment of aphasia in postcerebral infarction patients. Methods Patients were randomly divided into three groups: low-frequency rTMS(LF-rTMS)group(1 Hz), high-frequency rTMS(HF-rTMS)group(10 Hz), and speech training group. Patients language ability was assessed before treatment, 2, 4 and 12 weeks after treatment. Results The language ability in all three groups improved after treatment. Word-picture matching and aphasia quotients(AQ)reached the peak at 12 weeks and other indicators reached the peak at 4 weeks(P<0.05). Comparison among groups showed that the LF-rTMS group and HF-rTMS group exhibited a more marked improvement than the speech training group in each evaluation indicators at 2, 4 and 12 weeks after treatment(P<0.05). The view naming time of the HF-rTMS group was shorter than that of the LF-rTMS group at 2 and 4 weeks, but the scale of view naming of the LF-rTMS group was better than that of the HF-rTMS group at 2, 4 and 12 weeks(P<0.05). Conclusion Both LF-rTMS and HF-rTMS are beneficial to the recovery of linguistic function in cerebral infarction patients with non-fluent aphasia. The naming time of the HF-rTMS group is shorter, but the scale of naming of the LF-rTMS group is higher.

Key words: Repetitive transcranial magnetic stimulation, High-frequency, Low-frequency, Cerebral infarction, Aphasia

中图分类号: 

  • R574
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