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山东大学学报 (医学版) ›› 2022, Vol. 60 ›› Issue (11): 23-27.doi: 10.6040/j.issn.1671-7554.0.2022.0978

• 胸外科肺癌、食管癌微创诊治和加速康复专题 • 上一篇    下一篇

微创袖式肺叶切除手术：免疫治疗时代的机遇和挑战

高会江,魏煜程*()   

  1. 青岛大学附属医院胸外科, 山东 青岛 266003
  • 收稿日期:2022-08-18 出版日期:2022-11-01 发布日期:2022-11-04
  • 通讯作者: 魏煜程 E-mail:weiyuchengchest@163.com
  • 作者简介:魏煜程，主任医师，医学博士，硕士研究生导师。青岛大学附属医院胸外科副主任，西海岸院区胸外科主任。担任中国抗癌协会纵隔肿瘤专业委员会常委，中国老年保健协会肺癌专业委员会常委，山东省中青年肺癌联盟副主任委员，山东省临床肿瘤学会食管癌专家委员会副主任委员，青岛市抗癌协会胸部肿瘤专业委员会主任委员，MEDIASTINUM杂志编委。长期致力于胸部肿瘤的微创手术治疗及复杂局部晚期胸部肿瘤的外科手术及综合治疗。2012年受邀参加英国皇家外科学院举行的欧洲腔镜肺叶切除20周年纪念大会，做大会发言，获“Master of Thoracic Surgery”称号。以第一作者及通讯作者在《Annals of Thoracic Surgery》《Journal of Thoracic Disease》《Thoracic Cancer》及《中华外科杂志》《中华胸心外科杂志》《中国肺癌杂志》等专业学术期刊发表论文20余篇，累计影响因子30余分。培养硕士研究生20余人
  • 基金资助:
    青岛大学附属医院青年基金(QDFYQN 202101013)

Minimally invasive sleeve lobectomy: opportunities and challenges in the era of immunotherapy

Huijiang GAO,Yucheng WEI*()   

  1. Department of Thoracic Surgery, The Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong, China
  • Received:2022-08-18 Online:2022-11-01 Published:2022-11-04
  • Contact: Yucheng WEI E-mail:weiyuchengchest@163.com

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摘要：

袖式肺叶切除手术是局部晚期可切除中央型肺癌的一种标准治疗方式。与全肺切除手术相比，袖式肺叶切除手术可以在不影响患者生存的前提下，最大限度地通过保留肺组织而改善患者的生活质量。尽管支气管袖式肺叶切除增加了手术难度，但随着胸腔镜以及机器人技术的发展，微创袖式肺叶切除手术已经成为胸外科的常规术式。目前，随着免疫治疗在肺癌新辅助以及诱导治疗领域中的研究进展，越来越多的局部晚期可切除或潜在可切除的肺癌通过免疫治疗获得了根治的机会，这在改善患者预后的同时也为胸外科微创手术，尤其是微创袖式肺叶切除手术提出了更高的要求。本文对微创袖式肺叶切除手术的现状进行系统阐述以及前景展望。

关键词: 中央型肺癌, 微创, 袖式肺叶切除, 免疫治疗, 生存

Abstract:

Sleeve lobectomy, as a standard treatment for locally advanced resectable central lung cancer, can maximize the preservation of lung tissue and improve patients' quality of life without affecting survival, compared with total pneumonectomy. With the development of thoracoscopic and robotic technology, minimally invasive sleeve lobectomy has become a routine procedure in thoracic surgery, although bronchial sleeve lobectomy has increased the difficulty of operation. At present, with the development of immunotherapy in the field of neoadjuvant and induction therapy for lung cancer, a growing number of locally advanced resectable or potentially resectable lung cancer has been treated with immunotherapy. This not only improves the prognosis of patients, but also puts forward higher requirements for minimally invasive thoracic surgery, especially minimally invasive sleeve lobectomy. In this paper, the current situation of minimally invasive sleeve lobectomy is systematically described and the prospect is prospected.

Key words: Centrally-located lung cancer, Minimally invasive, Sleeve lobectomy, Immunotherapy, Survival

中图分类号: 

  • R734.2
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