老年功能区矢状窦旁巨大脑膜瘤的显微手术治疗

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doi:10.6040/j.issn.1671-7554.0.2019.500

摘要： 目的探讨显微手术切除老年矢状窦旁巨大脑膜瘤的临床效果。方法对2014年1月至2018年6月显微手术治疗的32例年龄>60岁［中位年龄(63.4±2.5)岁,最大年龄78岁］、累及功能区皮层的矢状窦旁巨大脑膜瘤(瘤径>5 cm)患者的临床资料进行回顾性分析,了解神经电生理监测联合显微外科技术的手术效果,总结治疗方法及手术技巧。结果术前合并高血压11例、冠心病5例、糖尿病8例、颅内血管狭窄4例、脊髓空洞2例,无合并症2例;手术全程进行运动/感觉诱发电位监测;Simpson I级切除11例,Simpson II级切除9例(其中2例为复发脑膜瘤),Simpson III级切除9例(其中3例为复发脑膜瘤),Simpson IV级切除3例(其中2例为复发脑膜瘤)。对WHO病理分级II级、III级和肿瘤残留、肿瘤细胞呈增生活跃状态的I级脑膜瘤,术后常规进行放射治疗。随访4~43个月,其中1例随访11个月时复发,再次手术后辅助放射治疗。无手术死亡病例。术前以偏瘫、偏身感觉障碍为主要表现14例,经治疗后恢复12例,术前无偏瘫术后出现偏瘫3例,其中1例并发肺炎,治疗后在7~21 d内恢复;以癫痫为主要症状8例患者术后口服抗癫痫药物,均未再出现癫痫发作。结论显微手术切除功能区老年矢状窦旁巨大脑膜瘤,术中强调使用神经电生理监测技术,保护功能区皮层组织和引流静脉;老年患者术后并发症多,影响术后整体治疗质量,围手术期必须高度重视合并症和并发症的防治。

关键词: 矢状窦旁脑膜瘤, 功能区, 老年

Abstract: Objective To investigate the clinical efficacy of microsurgery in the resection of giant para-sagittal meningioma in the elderly. Methods The clinical data of 32 elderly patients with giant meningioma(diameter >5 cm)involving the cortex of the functional area treated with microsurgery in our hospital during Jan. 2014 and Aug. 2018 were retrospectively analyzed. The patients aged >60 years(mean 63.4±2.5 years, maximum 78 years). The clinical outcomes and surgical skills were summarized. Results Hypertension was detected in 11 cases, coronary heart disease in 5 cases, diabetes mellitus in 8 cases, intracranial vascular stenosis in 4 cases, syringomyelia in 2 cases, and 2 cases had no complications. Motor/sensory evoked potentials were monitored throughout the operation. Simpson I resection was performed in 11 cases, Simpson II resection in 9 cases(2 cases were recurrent meningioma), Simpson III resections in 9 cases(3 cases were recurrent meningioma), and Simpson IV resection in 3 cases(2 cases were recurrent meningioma). Patients with WHO II tumor, WHO III tumor, residual tumor, or meningioma with active proliferative tumor cells received radiotherapy after operation. During the follow-up of 4-43 months, 1 case had relapse in month 11 and recov- 山东大学学报 (医学版)57卷11期 -田海龙,等.老年功能区矢状窦旁巨大脑膜瘤的显微手术治疗 \=-ered after a second operation and adjuvant radiotherapy. In no-death cases during operation, 14 manifested with hemiplegia and hemidysesthesia, in which 12 recovered; 3 cases developed hemiplegia, 1 of which was complicated with pneumonia, and recovered after 7-21 days; 8 patients with epilepsy took antiepileptic drugs and no seizure recurred. Conclusion In the microsurgical excision of giant para-sagittal meningioma in elderly patients, the protection of cortex and drainage veins in functional area is very important. As the complications affect clinical outcomes, due attention should be paid to the perioperative comorbidities and complications.

Key words: Para-sagittal meningioma, Functional area, Elderly

中图分类号:

R739.45

田海龙,危兆胜,刘斌,郭文强,张红英,王超超,王志刚. 老年功能区矢状窦旁巨大脑膜瘤的显微手术治疗[J]. 山东大学学报 (医学版), 2019, 57(11): 16-19.

TIAN Hailong, WEI Zhaosheng, LIU Bin, GUO Wenqiang, ZHANG Hongying, WANG Chaochao, WANG Zhigang. Microsurgical resection of giant para-sagittal meningioma in the functional area in the elderly[J]. Journal of Shandong University (Health Sciences), 2019, 57(11): 16-19.

[1] Bateman BT, Pile-Spellman J, Gutin PH, et al. Meningioma resection in the elderly: nationwide inpatient sample, 1998-2002[J]. Neurosurgery, 2005, 57(5): 866-872.
[2] 陈福业, 周汉, 丰育功, 等. 非典型脑膜瘤74例临床预后分析[J]. 中华神经外科疾病研究杂志, 2018, 17(1): 46-50. CHEN Fuye, ZHOU Han, FENG Yugong, et al. Clinical prognosis analysis of 74 patients with atypical meningioma[J]. Chinese Journal of Neurosurgical Disease Research, 2018, 17(1): 46-50.
[3] 刘宏斌, 吴涛, 周厚杰, 等. 上矢状窦旁脑膜瘤显微手术治疗22例分析[J]. 中国临床神经外科杂志, 2018, 23(3): 206-207. LIU Hongbin, WU Tao, ZHOU Houjie, et al. Microsurgical treatment of supra-sagittal meningioma: a report of 22 cases[J]. Chinese Journal of Clinical Neurosurgery, 2018, 23(3): 206-207.
[4] 杨勇灵. 显微手术治疗老年矢状窦旁及大脑镰旁脑膜瘤患者疗效[J].中国老年学杂志, 2014, 34(8): 4551-4553. YANG Yongling. The curative effect of microsurgery in elderly patients with perisagittal sinus meningioma and parafalx meningioma[J]. Chinese Journal of Gerontology, 2014, 34(8): 4551-4553.
[5] 王志明, 袁进国, 曹藏柱, 等. 老年患者大型脑膜瘤手术治疗36例临床分析[J]. 中国肿瘤临床与康复, 2009, 16(5): 436-437. WANG Zhiming, YUAN Jinguo, CAO Zangzhu, et al. Clinical analysis of 36 cases of large-scale meningioma in the elderly[J]. Chinese Oncology Clinical and Rehabilitation, 2009, 16(5): 436-437.
[6] Kleib AS, Ngaidé BH, Eleit AEM, et al. Surgical treatment of intracranial meningiomas in Nouakchott, Mauritania[J]. Pan Afr Med J, 2018, 31: 146. doi: 10.11604/pamj.2018.31.146.16485.
[7] Czigléczki G, Németh F, Berényi G,et al.Prognostic factors of surgically treated spinal meningeomas and long-term surgical outcomes[J]. Ideggyogy Sz, 2019, 72(3-4): 93-97.
[8] 赵鹏来, 罗正祥, 张岩松, 等. 中央回区矢状窦旁脑膜瘤的术前影响评估和显微外科治疗[J]. 中华神经外科杂志, 2015, 31(2): 184-187. ZHAO Penglai, LUO Zhengxiang, ZHANG Yansong, et al. Preoperative impact assessment and microsurgical treatment of apantral meningioma in the central gyrus region[J]. Chinese Journal of Neurosurgery, 2015, 31(2): 184-187.
[9] Kreβner M, Arlt F, Riepl W, et al. Prognostic factors of microsurgical treatment of intracranial meningiomas—a multivariate analysis[J]. PLoS One, 2018, 13(10): e0202520. doi: 10.1371/journal.pone.0202520.
[10] Da Silva CE, de Freitas PEP. Surgical removal of skull base meningiomas in symptomatic elderly patients[J]. World Neurosurg, 2018, 120: e1149-1155. doi: 10.1016/j.wneu.2018.09.024.

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