裂萼苔水生变种化学成分

doi:10.6040/j.issn.1671-7554.0.2019.053

摘要/Abstract

摘要： 目的分离并鉴定苔藓植物裂萼苔水生变种中的化学成分。方法利用MCI柱层析、硅胶柱层析、凝胶柱层析、半制备HPLC等技术手段对裂萼苔样品进行分离纯化,利用NMR、HRESIMS等波谱数据进行结构解析和鉴定。结果从该植物中分离得到5个化合物,包括2个新的桉烷型倍半萜,分别命名为(3S,7R,10S)-7-hydroxy-3-methoxy-eudesma-4E-ene(1)和(3S,7R,10S)-7-hydroxy-3-ethyoxyl-eudesma-4E-ene(2),1个愈创木烷型倍半萜(guaianediol,3),1个半日花烷型二萜(nivenolide,4)以及1个羽扇豆烷型三萜(betulin,5)。结论 1和2为新化合物, 3~5为首次从裂萼苔属植物中分离出来的已知化合物。

关键词: 苔藓植物, 裂萼苔水生变种, 桉烷型倍半萜, 愈创木烷型倍半萜, 二萜, 三萜

Abstract: Objective To study the chemical constituents of Chiloscyphus polyanthus var. rivularis. Methods The chemical constituents were isolated and identified on the basis of various chromatographic methods such as MCI gel, silica gel, Sephadex LH-20 column, and semi-preparation HPLC as well as a combination of their spectroscopic data, such as NMR and HRESIMS. Results Isolation of Chiloscyphus polyanthus var. rivularis afforded five compounds, including two new eudesmane type sesquiterpenoids, which were named (3S,7R,10S)-7-hydroxy-3-methoxy-eudesma-4E-ene(1)and (3S,7R,10S)-7-hydroxy-3-ethyoxyl-eudesma-4E-ene(2), one guaiane type sesquiterpenoid(guaianediol, 3), one labdane-type diterpenoid(nivenolide, 4), and one triterpenoid(betulin, 5). Conclusion Compounds 1 and 2 are previously undescribed and compounds 3-5 are isolated from the plants in genus Chiloscyphus for the first time.

Key words: Bryophytes, Chiloscyphus polyanthus var. rivularis, Eudesmane type sesquiterpenoids, Guaiane type sesquiterpenoid, Diterpenoid, Triterpenoid

中图分类号:

R574

张教真,娄红祥. 裂萼苔水生变种化学成分[J]. 山东大学学报 (医学版), 2019, 57(3): 38-41.

ZHANG Jiaozhen, LOU Hongxiang. Chemical constituents of Chiloscyphus polyanthus var. rivularis[J]. Journal of Shandong University (Health Sciences), 2019, 57(3): 38-41.

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