您的位置：山东大学 -> 科技期刊社 -> 《山东大学学报（医学版）》

山东大学学报 (医学版) ›› 2021, Vol. 59 ›› Issue (7): 91-96.doi: 10.6040/j.issn.1671-7554.0.2021.0168

• • 上一篇    

结直肠癌术后患者人格特质与抑郁、焦虑症状的关联性

孙富云1,2,王维鹏1,3,张会会1,耿艳1,安小霞1,李双双1,张彬彬1,4   

  • 发布日期:2021-07-16
  • 通讯作者: 张彬彬. E-mail:zhangbinbinql@163.com
  • 基金资助:
    山东省重点研发计划(公益性科技攻关)(2019GSF108151);山东大学齐鲁医学院本科教学改革与研究项目(qlyxjy-201944)

Correlation among personality traits and depression, anxiety symptoms in patients after colorectal cancer resection

SUN Fuyun1,2, WANG Weipeng1,3, ZHANG Huihui1, GENG Yan1, AN Xiaoxia1, LI Shuangshuang1, ZHANG Binbin1,4   

  1. 1. Department of General Surgery, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China;
    2. Cheeloo College of Medicine, Shandong University, Jinan 250012, Shandong, China;
    3. College of Nursing, Jining Medical University, Jining 272067, Shandong, China;
    4. Nursing Theory &
    Practice Innovation Research Center of Shandong University, Jinan 250012, Shandong, China
  • Published:2021-07-16

PDF (PC)

164

摘要： 目的 探讨结直肠癌术后患者人格特质特征与抑郁、焦虑症状的关联性。 方法 选取2018年2月至12月在山东大学齐鲁医院普外科住院的结直肠癌术后患者162例,采用一般情况调查表、医院焦虑抑郁量表、艾森克人格测验成人版、生活方式自评量表于出院前1日分别测量患者的一般情况,抑郁、焦虑症状,外向性、神经质或情绪、精神病性、人格稳定性,生活方式健康状况,使用多元线性回归进行统计分析。 结果 结直肠癌术后患者中,有37.0%存在抑郁症状,40.2%存在焦虑症状。多元线性回归分析结果显示,外向性得分与抑郁(β=-0.492,P<0.001)、焦虑症状(β=-0.336,P<0.001)得分呈负向关联,神经质/情绪得分与抑郁(β=0.166,P=0.016)、焦虑症状(β=0.345,P<0.001)得分呈正向关联。 结论 结直肠癌术后患者的抑郁、焦虑症状、阳性率较高。患者越外向,其抑郁、焦虑症状越轻;越神经质,其抑郁、焦虑症状越严重。

关键词: 结直肠癌, 外向性, 神经质/情绪, 抑郁症状, 焦虑症状

Abstract: Objective To explore the correlation among personality traits and depression, anxiety symptoms in patients after colorectal cancer resection. Methods Totally 162 patients with colorectal cancer hospitalized in Department of General Surgery, Qilu Hospital of Shandong University from Feb. to Dec. 2018 were assessed before discharge with General Condition Questionnaire, Hospital Anxiety and Depression Scale, Eysenck Personality Questionnaire, and Lifestyle Self-Rating Scale, to measure the general condition, depression and anxiety symptoms, extraversion, neuroticism, psychoticism, personality stability, and health condition of living style. Data collected were analyzed with multiple linear regression. Results Depression and anxiety symptoms were reported by 37.0% and 40.2% patients, respectively. Multiple linear regression suggested that extraversion was negatively correlated with depression(β=-0.492, P<0.001)and anxiety symptoms(β=-0.336, P<0.001), while neuroticism was positively correlated with depression(β=0.166, P=0.016)and anxiety symptoms(β=0.345, P<0.001). Conclusion The positive rates of the depression and anxiety symptoms are high in patients after colorectal cancer resection. Extroversion is negatively correlated with depression and anxiety symptoms, while neuroticism is positively correlated with depression and anxiety symptoms.

Key words: Colorectal cancer, Extraversion, Neuroticism, Depression symptoms, Anxiety symptoms

中图分类号: 

  • R395.1
[1] American Cancer Society. Cancer Facts & Figures 2020 [M]. Atlanta: American Cancer Society, 2020:15.
[2] Peng YN, Huang ML, Kao CH. Prevalence of Depression and Anxiety in Colorectal Cancer Patients: A Literature Review [J]. Int J Environ Res Public Health, 2019, 16(3): 411. doi: 10.3390/ijerph16030411.
[3] Gray NM, Hall SJ, Browne S, et al. Predictors of anxiety and depression in people with colorectal cancer [J]. Support Care Cancer, 2014, 22(2): 307-314.
[4] 汪翠云, 王维利, 汪苗. 105例结直肠癌术后患者生活质量调查及影响因素分析[J]. 护理学报, 2012, 19(2): 12-15. WANG Cuiyun, WANG Weili, WANG Miao. Survey on quality of life of 105 postoperative patients with colorectal cancer and analysis of its influencing factors [J]. Journal of Nursing, 2012, 19(2): 12-15.
[5] 颜斐斐, 张立力. 结直肠癌术后患者癌因性疲乏与焦虑抑郁关系的研究[J]. 护理学杂志, 2009, 24(8): 83-85. YAN Feifei, ZHANG Lili. Cancer-related fatigue, anxiety and depression in postoperative colorectal cancer patients [J]. Journal of Nursing Science, 2009, 24(8): 83-85.
[6] Mols F, Schoormans D, de Hingh I, et al. Symptoms of anxiety and depression among colorectal cancer survivors from the population-based, longitudinal PROFILES Registry: Prevalence, predictors, and impact on quality of life [J]. Cancer, 2018, 124(12): 2621-2628.
[7] Glavic Z, Galic S, Krip M. Quality of life and personality traits in patients with colorectal cancer [J]. Psychiatr Danub, 2014, 26(2): 172-180.
[8] Sharma A, Sharp DM, Walker LG, et al. Patient personality predicts postoperative stay after colorectal cancer resection [J]. Colorectal Dis, 2008, 10(2): 151-156.
[9] 郑磊磊, 王也玲, 李惠春. 医院焦虑抑郁量表在综合性医院中的应用[J]. 上海精神医学, 2003, 15(5): 264-266. ZHENG Leilei, WANG Yeling, LI Huichun. Application of Hospitai Anxiety and Depression Scale In general hospital: an analysisi in reliability and validity [J]. General Psychiatry, 2003, 15(5): 264-266.
[10] Zigmond AS, Snaith RP. The Hospital Anxiety and Depression Scale [J]. Acta Psychiatr Scand, 1983, 67(6): 361-370.
[11] 陈仲庚. 艾森克人格问卷的项目分析[J]. 心理学报, 1983, 15(2): 85-92. CHEN Zhonggeng. Item analysis of Eysenck Personality Questionnaire [J]. Journal of Psychology, 1983, 15(2): 85-92.
[12] 姜丽萍. 上海市女大学生生活方式与心理健康的相关研究[D]. 上海:华东师范大学, 2006.
[13] 吕乐. 艾森克人格问卷第二次常模样本的信度和效度研究[D]. 长沙: 中南大学, 2008.
[14] Hengartner MP, Ajdacic-Gross V, Wyss C, et al. Relationship between personality and psychopathology in a longitudinal community study: a test of the predisposition model [J]. Psychol Med, 2016, 46(8): 1693-1705.
[15] Macía P, Gorbeña S, Gómez A, et al. Role of neuroticism and extraversion in the emotional health of people with cancer [J]. Heliyon, 2020, 6(7): e04281. doi: 10.1016/j.heliyon.2020.e04281.
[16] Cuki c I, Weiss A. Personality and diabetes mellitus incidence in a national sample [J]. J Psychosom Res, 2014, 77(3): 163-168.
[17] Perry LM, Hoerger M, Silberstein J, et al. Understanding the distressed prostate cancer patient: role of personality [J]. Psychooncology, 2018, 27(3): 810-816.
[18] Muscatello MR, Bruno A, Mento C, et al. Personality traits and emotional patterns in irritable bowel syndrome [J]. World Journal of Gastroenterology, 2016, 22(28): 6402-6415.
[19] Vinkhuyzen AA, Pedersen NL, Yang J, et al. Common SNPs explain some of the variation in the personality dimensions of neuroticism and extraversion [J]. Transl Psychiatry, 2012, 2(4): e102. doi: 10.1038/tp.2012.27.
[1] 李宁,李娟,谢艳,李培龙,王允山,杜鲁涛,王传新. 长链非编码RNA AL109955.1在80例结直肠癌组织中的表达及对细胞增殖与迁移侵袭的影响[J]. 山东大学学报 (医学版), 2020, 1(7): 38-46.
[2] 吕岩,于潇,蔺新英,赵琦,王保珍. 聊城市老年女性膳食模式与抑郁症状的关系[J]. 山东大学学报 (医学版), 2020, 58(11): 103-108.
[3] 方茜, 曲爱林, 张欣, 杜鲁涛, 杨咏梅, 王传新. 血清miR-210在结直肠癌患者血清中的表达及临床意义[J]. 山东大学学报（医学版）, 2015, 53(6): 77-81.
[4] 刘成霞, 李明, 连海峰, 史宁. miRNA-486-5p对结肠癌细胞株SW620生物学行为的影响[J]. 山东大学学报（医学版）, 2015, 53(1): 16-20.
[5] 李剑萍, 缪宇锋, 陈平, 陈苏蓉, 刘红旗. 雷替曲塞联合奥沙利铂或伊立替康二线治疗晚期结直肠癌的临床观察[J]. 山东大学学报（医学版）, 2014, 52(S1): 49-50.
[6] 张艳丽, 刘新风, 张欣, 王海燕, 杨咏梅, 杜鲁涛, 王丽丽, 李培龙, 王传新. 循环miR-128在结直肠癌患者血清中的表达及其对细胞迁移侵袭能力的影响[J]. 山东大学学报（医学版）, 2014, 52(8): 57-62.
[7] 刘文辉, 李晓玲, 袁萍, 栾荣生, 冯斐, 胡晓琴, 燕锦, 杨艳芳. 脂联素基因和钙蛋白酶10基因多态性与结直肠癌发生风险的关系[J]. 山东大学学报（医学版）, 2014, 52(11): 106-112.
[8] 冯斐1，燕锦2，袁萍1，胡晓琴1，徐琳2，杨艳芳1. 饮食习惯、生活方式与结直肠癌关系的配对病例对照研究[J]. 山东大学学报(医学版), 2013, 51(7): 107-112.
[9] 刘慧，杜鲁涛，杨咏梅，董召刚，李娟，刘益民，张欣，王丽丽，郑桂喜，王传新. MiR-182在结直肠癌中的表达及其对结直肠癌细胞迁移能力的影响[J]. 山东大学学报(医学版), 2013, 51(12): 70-74.
[10] 樊智彬1，于卫芳2,张丽静1，刘博1，吴晨鹏3，张学明4，赵增仁1. microRNA-150在结直肠癌组织中的表达及临床意义[J]. 山东大学学报(医学版), 2013, 51(11): 85-89.
[11] 袁志平1，牟华平2，王秋1，王立帅1，陈洁1，张川利1，周光远1，陈家莲1. VEGF、sICAM-1蛋白在结直肠癌患者血清中的表达水平及临床意义[J]. 山东大学学报(医学版), 2013, 51(10): 74-76.
[12] 魏倩倩1， 焦志安2，高进2，赵国庆2. 焦虑症状对抑郁症治疗效果的影响[J]. 山东大学学报(医学版), 2012, 50(9): 113-117.
[13] 赵增仁1，张丽静1，张志勇2，郑峥1，王园园1，孙晓锋1. 结直肠癌中p53、Nup88的表达及其相关性[J]. 山东大学学报(医学版), 2011, 49(4): 105-109.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
版权所有 © 2018 《山东大学学报(医学版)》编辑部　
地址:山东大学科技期刊社（济南市历城区山大南路27号山东大学中心校区明德楼B座721室） 电话: 0531-88366918 E-mail: xbyxb@sdu.edu.cn
本系统由北京玛格泰克科技发展有限公司设计开发