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山东大学学报 (医学版) ›› 2020, Vol. 58 ›› Issue (8): 28-33.doi: 10.6040/j.issn.1671-7554.0.2020.1012

• 脑科学与类脑智能研究专题 • 上一篇    下一篇

4D数字脑图谱的构建、不对称性及遗传倾向

刘树伟1,2,*(),娄云霞1,2,汤煜春1,2   

  1. 1. 山东大学齐鲁医学院断层影像解剖学研究中心, 山东大学基础医学院, 山东大学数字人研究院，山东 济南 250012
    2. 山东大学脑与类脑科学研究院，山东 济南 250012
  • 收稿日期:2020-06-24 出版日期:2020-08-07 发布日期:2020-08-07
  • 通讯作者: 刘树伟 E-mail:liusw@sdu.edu.cn
  • 作者简介:刘树伟，医学博士，山东大学特聘教授，博士研究生导师。现任山东大学基础医学院神经科学中心主任、山东大学数字人研究院院长、山东大学脑与类脑科学研究院副院长，曾任山东大学研究生院常务副院长、医学院副院长，兼任亚洲临床解剖学会副主席、中国解剖学会副理事长和断层影像解剖学分会主任委员等职。获卫生部有突出贡献的中青年专家和山东省教学名师称号，享受国务院政府特殊津贴|潜心断层影像解剖学、数字人体、数字脑图谱和胎儿脑发育研究，承担国家及省部级课题20余项，在《Cerebral Cortex》《Radiology》《NeuroImage》等期刊发表论文300余篇(其中SCI收录70余篇)，主编《人体断层解剖学》《临床中枢神经解剖学》《功能神经影像学》等著作34部，获省部级科技进步奖4项(其中一等奖1项)。长期从事人体解剖学教学，创建了断层解剖学课程和数字解剖学教学体系，获国家级教学成果奖二等奖2项，主编《断层解剖学》和《局部解剖学》全国规划教材，主译了世界解剖学名著《格氏解剖学》(第41版)
  • 基金资助:
    国家自然科学基金(81371533);国家自然科学基金(31771328);山东省重点研发计划(2017CXGC1501)

The construction, asymmetry and genetic correlation of 4D digital brain atlas

Shuwei LIU1,2,*(),Yunxia LOU1,2,Yuchun TANG1,2   

  1. 1. Research Center for Sectional and Imaging Anatomy, Cheeloo College of Medicine, Shandong University, School of Basic Medical Sciences, Shandong University, Digital Human Institute, Shandong University, Jinan 250012, Shandong, China
    2. Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, Shandong, China
  • Received:2020-06-24 Online:2020-08-07 Published:2020-08-07
  • Contact: Shuwei LIU E-mail:liusw@sdu.edu.cn

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摘要：

人脑图谱是研究大脑结构和功能的基本工具，是进行脑结构和功能信息分析处理的重要手段。构建不同年龄段、不同性别、不同颅脑分型的标准化4D脑图谱，并利用计算机技术进行可视化和大脑结构的动态分析，可以为人脑结构和功能的发育及发展变化提供详实的形态学基础。概述4D数字脑图谱的构建、不对称性及其遗传倾向，并对未来的研究方向进行展望。

关键词: 数字化, 脑图谱, 脑模板, 不对称性, 遗传倾向

Abstract:

Human Brain Mapping is an important tool for exploring the structure and function of human brains, and is the basic platform for analyzing and processing brain structure and function information. The establishment of standardized 4D brain maps of different ages, genders and brain types, and the use of computer technology for visualization and dynamic analysis of brain structure can provide a detailed morphological basis for the embryogenesis and development of human brain structure and function. In this review, we present recent studies regarding the construction, asymmetry and genetic correlation of 4D digital brain atlas. Finally, discussions on the future research directions of brain atlas are given.

Key words: Digital, Brain atlas, Brain template, Asymmetry, Genetic correlation

中图分类号: 

  • R338.1
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