您的位置:山东大学 -> 科技期刊社 -> 《山东大学学报(医学版)》

山东大学学报(医学版) ›› 2009, Vol. 47 ›› Issue (12): 9-12.

• 论文 • 上一篇    下一篇

糖尿病与冠心病患者心率恢复异常及其对冠心病的诊断价值

张玉红,李贵双,李海德   

  1. 教育部和卫生部心血管重构和功能研究重点实验室 山东大学齐鲁医院心内科,  济南  250012
  • 收稿日期:2009-09-22 出版日期:2009-12-16 发布日期:2009-12-16
  • 通讯作者: 李贵双(1963- ),男,博士,副教授,研究方向为超声心动图及冠心病、先心病的介入治疗。 Email:lgs630322@yahoo.com.cn
  • 作者简介:张玉红(1984- ),女,硕士研究生,研究方向为超声心动图及冠心病、先心病的介入治疗。

Abnormal heart rate recovery in patients with diabetes mellitus or coronary heart disease and its diagnostic value for coronary heart disease

ZHANG Yuhong, LI Guishuang, LI Haide   

  1. Key Laboratory of Cardiovascular Remodeling and Function Research,  Chinese Ministry of
    Education and Chinese Ministry of Public Health; Department of Cardiology,
    Qilu Hospital, Shandong University, Jinan 250012, China
  • Received:2009-09-22 Online:2009-12-16 Published:2009-12-16

摘要:

目的探讨冠心病、糖尿病患者对平板运动试验后心率恢复的影响以及心率恢复异常对无症状的糖尿病患者合并冠心病的诊断价值。方法对88例拟诊冠心病患者行平板运动试验,以糖尿病史及血糖水平分为非糖尿病组(n=45)、糖尿病组(n=43)。根据冠脉造影结果,非糖尿病组分为非冠心病组(A组,n=22)和冠心病组(B组,n=23),糖尿病组分为非冠心病组(C组,n=22)和冠心病组(D组,n=21)。计算运动后1、2、3、4和5?min心率恢复值并进行比较。研究心率恢复异常对非糖尿病和糖尿病患者合并冠心病的诊断价值。结果平板运动后1、2、3、4和5?min心率恢复值由大到小依次为A、C、B和D组。与非糖尿病组相比,心率恢复异常诊断糖尿病所合并冠心病的灵敏性高,特异性和准确性无差别。结论冠心病对心率恢复的影响大于糖尿病,心率恢复异常可以作为筛选糖尿病患者是否合并冠心病的指标之一。

关键词: 平板运动试验, 心率恢复, 糖尿病, 冠心病

Abstract:

To investigate the effect of diabetes mellitus(DM) and coronary heart disease(CHD) on heart rate recovery after the treadmill exercise test and the clinical value of heart rate recovery in diagnosing preclinical coronary heart disease in diabetics. Methods88 suspicious CHD patients who underwent the treadmill exercise test were divided into the nondiabetes mellitus (NDM) group(n=45) and DM group(n=43) according to a history of diabetes mellitus and blood glucose levels. Based on a coronary artery angiogram, the NDM group was divided into the noncoronary heart disease (NCHD) group (group A, n=22) and CHD group (group B, n=23), while the DM group was divided into the NCHD group (group C, n=22) and CHD group (group D, n=21). Heart rate recovery among the 4 groups was compared at 1,2,3,4 and 5?minutes after the test. The sensitivity and specificity of abnormal heart rate recovery were compared between the DM group and NDM group for the diagnosis of CHD. ResultsThe order of heart rate recovery after the treadmill exercise test at each time point of the 4 groups was Group A, C, B and D from high to low. The DM group and NDM group had the same specificity and accuracy of abnormal heart rate recovery for the diagnosis of CHD, but the former had higher sensitivity. ConclusionsThe influence of CHD on heart rate recovery was greater than that of DM. Abnormal heart rate recovery after the treadmill exercise test could be used to screen for CHD in diabetic patients.

Key words: Treadmill exercise test, Heart rate recovery, Diabetes mellitus, Coronary heart disease

中图分类号: 

  • R541.1
[1] 孔令群,王学文,王海滨,曹学峰,吴燕彬,张兴元. 副神经节瘤1例报告[J]. 山东大学学报 (医学版), 2020, 1(9): 110-112.
[2] 张宝文,雷香丽,李瑾娜,罗湘俊,邹容. miR-21-5p靶向调控TIMP3抑制2型糖尿病肾病小鼠肾脏系膜细胞增殖及细胞外基质堆积[J]. 山东大学学报 (医学版), 2020, 1(7): 7-14.
[3] 张亮,徐敏,庄向华,娄福臣,娄能俊,吕丽,郭文娟,郑凤杰,陈诗鸿. 内质网应激与凋亡在糖尿病周围神经病变中的表达变化[J]. 山东大学学报(医学版), 2017, 55(8): 13-17.
[4] 王春霞,许艺博,杨宁,夏冰,王萍,薛付忠. 基于健康管理队列的冠心病风险预测模型[J]. 山东大学学报(医学版), 2017, 55(6): 66-71.
[5] 苏萍,杨亚超,杨洋,季加东,阿力木·达依木,李敏,薛付忠,刘言训. 健康管理人群2型糖尿病发病风险预测模型[J]. 山东大学学报(医学版), 2017, 55(6): 82-86.
[6] 张振堂,杨洋,韩福俊,陈向华,季晓康,王永超,王淑康,孙苑潆,李敏,陈亚飞,王丽,薛付忠,刘言训. 基于社区2型糖尿病患者的心脑血管事件5年风险预测模型[J]. 山东大学学报(医学版), 2017, 55(6): 108-113.
[7] 李帅,王雅琳,孙忠文,朱梅佳. Nod样受体蛋白3炎性体在2型糖尿病脑微血管内皮细胞中的变化及变化机制[J]. 山东大学学报(医学版), 2017, 55(3): 6-11.
[8] 谢海滨,武群政,刘少壮,黄鑫,程玉刚,胡三元,张光永. 肝线粒体相关内质网膜在袖状胃切除术改善糖尿病大鼠胰岛素敏感性中的作用[J]. 山东大学学报(医学版), 2017, 55(10): 36-40.
[9] 巩璐伟,周丽珍,苏国海. 培哚普利通过调节Akt-FoxO1通路保护糖尿病性心肌病大鼠心功能损伤[J]. 山东大学学报(医学版), 2017, 55(10): 65-70.
[10] 杨洋,张光,张成琪,宋心红,薛付忠,王萍,王丽,刘言训. 基于体检队列的2型糖尿病风险预测模型[J]. 山东大学学报(医学版), 2016, 54(9): 69-72.
[11] 彭力,强晔,赵蕙琛,陈诗鸿,姚伟东,刘元涛. 2型糖尿病患者应用西格列汀的短期疗效及影响因素[J]. 山东大学学报(医学版), 2016, 54(8): 60-63.
[12] 林栋,管庆波. 2型糖尿病男性患者血清睾酮水平低下对非酒精性脂肪肝的影响[J]. 山东大学学报(医学版), 2016, 54(7): 33-37.
[13] 史蕊,孙佩,王璐璐,丁琳,夏金,王燕,逄曙光. 鼠神经生长因子联合维生素D、甲钴胺治疗糖尿病周围神经病变的临床观察[J]. 山东大学学报(医学版), 2016, 54(4): 64-67.
[14] 木哈达斯·吐尔逊依明,帕它木·莫合买提,托兰古丽·买买提库尔班. CDKAL1(rs10946398 C/A)基因多态性与2型糖尿病易感性关系Meta分析[J]. 山东大学学报(医学版), 2016, 54(2): 75-85.
[15] 于宁,高燕燕,咸玉欣,牛佳鹏,李莉,王静,曹彩霞. 艾塞那肽对2型糖尿病合并非酒精性脂肪肝患者肝脏脂肪含量及血清chemerin水平的影响[J]. 山东大学学报(医学版), 2016, 54(11): 51-55.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!